Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 Biomarker disease BEFREE Osteoprotegerin abrogated cortical porosity and bone marrow fibrosis in a mouse model of constitutive activation of the PTH/PTHrP receptor. 19389927 2009
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 AlteredExpression disease BEFREE We conclude that osteosclerosis in IMF is associated with increased endothelial OPG expression without concomitant RANKL downregulation. 15982347 2005
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 AlteredExpression disease BEFREE OPG mRNA expression in fibrotic IMF was correlated with TGF beta-1 mRNA expression in a case-specific manner. 15726648 2005
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 Biomarker disease BEFREE Gene knockout experiments using such animal models have suggested the essential role of hematopoietic cell-derived transforming growth factor beta1 in inducing bone marrow fibrosis and stromal cell-derived osteoprotegerin in promoting osteosclerosis. 16293880 2005
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 AlteredExpression disease LHGDN Osteosclerosis in idiopathic myelofibrosis is related to the overproduction of osteoprotegerin (OPG). 15504545 2004
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.050 Biomarker disease BEFREE Osteosclerosis in idiopathic myelofibrosis is related to the overproduction of osteoprotegerin (OPG). 15504545 2004