Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.510 Therapeutic phenotype RGD Beneficial effect of TGFbeta antagonism in treating diabetic nephropathy depends on when treatment is started. 16902320 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.510 Biomarker phenotype CTD_human Angiotensin-converting enzyme inhibition and angiotensin AT1 receptor blockade downregulate angiotensin-converting enzyme expression and attenuate renal injury in streptozotocin-induced diabetic rats. 23733546 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.510 GeneticVariation phenotype LHGDN Alpha-adducin and angiotensin-converting enzyme polymorphisms in hypertension: evidence for a joint influence on albuminuria. 16612256 2006
Entrez Id: 118
Gene Symbol: ADD1
ADD1
0.010 GeneticVariation phenotype LHGDN ADD1 polymorphisms per se were not associated with albuminuria. 16612256 2006
Entrez Id: 84890
Gene Symbol: ADO
ADO
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 177
Gene Symbol: AGER
AGER
0.200 Therapeutic phenotype RGD Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats. 21796806 2011
Entrez Id: 183
Gene Symbol: AGT
AGT
0.300 Biomarker phenotype CTD_human Silencing of hypoxia-inducible factor-1α gene attenuated angiotensin II-induced renal injury in Sprague-Dawley rats. 21896938 2011
Entrez Id: 183
Gene Symbol: AGT
AGT
0.300 Biomarker phenotype CTD_human A nonpeptide, piperidine renin inhibitor provides renal and cardiac protection in double-transgenic mice expressing human renin and angiotensinogen genes. 18679781 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
0.300 Biomarker phenotype CTD_human Immunosuppressive treatment protects against angiotensin II-induced renal damage. 12414515 2002
Entrez Id: 196
Gene Symbol: AHR
AHR
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 26289
Gene Symbol: AK5
AK5
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.200 Biomarker phenotype RGD Increased glomerular albumin permeability in old spontaneously hypertensive rats. 15102963 2004
Entrez Id: 364
Gene Symbol: AQP7
AQP7
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 54622
Gene Symbol: ARL15
ARL15
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 57597
Gene Symbol: BAHCC1
BAHCC1
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 56918
Gene Symbol: C2orf83
C2orf83
0.100 GeneticVariation phenotype GWASCAT Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion. 30910378 2019
Entrez Id: 834
Gene Symbol: CASP1
CASP1
0.300 Biomarker phenotype CTD_human Pathologically, hHcys-associated albuminuria, foot process effacement of podocytes, loss of podocyte slit diaphragm molecules, and glomerulosclerosis at the late stage were significantly improved by local ASC gene silencing or by caspase 1 inhibition. 22647887 2012
Entrez Id: 846
Gene Symbol: CASR
CASR
0.200 Biomarker phenotype RGD Interstitial fibrosis and microvascular disease of the heart in uremia: amelioration by a calcimimetic. 19188910 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.010 AlteredExpression phenotype LHGDN These results suggest that MCP-1 is produced in renal tubular cells and released into urine in proportion to the degree of proteinuria (albuminuria), and that increased MCP-1 expression in renal tubuli contributes to renal tubular damage. 12505750 2003
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
0.010 GeneticVariation phenotype LHGDN This study investigated whether the association of CCL5 and albuminuria is a general phenomenon. 18217191 2008
Entrez Id: 10576
Gene Symbol: CCT2
CCT2
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 952
Gene Symbol: CD38
CD38
0.300 Biomarker phenotype CTD_human This enhanced glomerular injury in CD38(-/-) or CD38-shRNA mice was accompanied by increased albuminuria and proteinuria. 21992601 2012
Entrez Id: 55636
Gene Symbol: CHD7
CHD7
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 1286
Gene Symbol: COL4A4
COL4A4
0.100 GeneticVariation phenotype GWASCAT Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. 30220432 2018
Entrez Id: 1356
Gene Symbol: CP
CP
0.300 Biomarker phenotype CTD_human Multivariate regression analysis demonstrated that elevated serum ceruloplasmin was a determinant of albuminuria independently of conventional risk factors. 21752484 2011