Gene: NUDT15 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE Genotyping of NUDT15 codon 139 was sufficient to predict acute severe leukopenia and alopecia in Japanese patients with IBD. 29923122 2018
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE Severe thiopurine-induced leukocytopenia and hair loss in Japanese patients with defective NUDT15 variant: Retrospective case-control study. 30101994 2018
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease GWASCAT NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. 29923122 2018
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE NUDT15 p.R139C was strongly associated with early leukopenia and severe alopecia (OR for early leukopenia: 107.624, 95% CI 18.857-614.250, p=1.403 × 10<sup>-7</sup>, OR for severe alopecia: 77.152, 95% CI 17.378-342.526, p=1.101 × 10<sup>-8</sup>). 28566182 2017
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE Extensive hair loss was a recognizable early symptom in patients with the homozygous NUDT15 c.415C>T variant. 26735160 2016
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE NUDT15 rs116855232" genes_norm="55270">R139C (rs116855232) is a recently identified genetic factor responsible for thiopurine-induced leukocytopenia and hair loss. 26590936 2016
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15 		0.160 GeneticVariation disease BEFREE NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD. 26076924 2016