Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 643680
Gene Symbol: MS4A4E
MS4A4E
0.140 GeneticVariation disease BEFREE Genome-wide association studies and meta-analyses implicated that increased risk of developing Alzheimer's diseases (AD) has been associated with the ABCA7, APOE, BIN1, CASS4, CD2AP, CD33, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB1, HLA-DRB4, INPP5D, MEF2C, MS4A4A, MS4A4E, MS4A6E, NME8, PICALM, PLD3, PTK2B, RIN3, SLC24A4, SORL1, and ZCWPW1 genes. 28199971 2017
Entrez Id: 643680
Gene Symbol: MS4A4E
MS4A4E
0.140 GeneticVariation disease BEFREE We estimated an 8% decrease in Alzheimer's disease incidence without CLU-MS4A4E risk alleles and identified potential causal variants. 26449541 2016
Entrez Id: 643680
Gene Symbol: MS4A4E
MS4A4E
0.140 GeneticVariation disease BEFREE To examine whether there is a genetic link for these diseases, we performed a case-control study in Chinese population to evaluate the association of AD genome-wide association studies top hits with both PD and cognitive function in PD, investigating 13 single-nucleotide polymorphisms in 9 genes (BIN1, CLU, ABCA7, CR1, PICALM, MS4A6A, CD33, MS4A4E, and CD2AP). 26724962 2016
Entrez Id: 643680
Gene Symbol: MS4A4E
MS4A4E
0.140 GeneticVariation disease BEFREE Our study verified the association between PICALM, BIN1, CLU, and MS4A4E variants and AD susceptibility in Han Chinese populations. 25452228 2016
Entrez Id: 643680
Gene Symbol: MS4A4E
MS4A4E
0.140 GeneticVariation disease GWASDB Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 21460841 2011