×
Entrez Id:
643680
Gene Symbol:
MS4A4E
MS4A4E
0.140
GeneticVariation
disease
BEFREE
Genome-wide association studies and meta-analyses implicated that increased risk of developing Alzheimer's diseases (AD) has been associated with the ABCA7, APOE, BIN1, CASS4, CD2AP, CD33, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB1, HLA-DRB4, INPP5D, MEF2C, MS4A4A, MS4A4E , MS4A6E, NME8, PICALM, PLD3, PTK2B, RIN3, SLC24A4, SORL1, and ZCWPW1 genes.
28199971
2017
×
Entrez Id:
643680
Gene Symbol:
MS4A4E
MS4A4E
0.140
GeneticVariation
disease
BEFREE
We estimated an 8% decrease in Alzheimer's disease incidence without CLU-MS4A4E risk alleles and identified potential causal variants.
26449541
2016
×
Entrez Id:
643680
Gene Symbol:
MS4A4E
MS4A4E
0.140
GeneticVariation
disease
BEFREE
To examine whether there is a genetic link for these diseases, we performed a case-control study in Chinese population to evaluate the association of AD genome-wide association studies top hits with both PD and cognitive function in PD, investigating 13 single-nucleotide polymorphisms in 9 genes (BIN1, CLU, ABCA7, CR1, PICALM, MS4A6A, CD33, MS4A4E , and CD2AP).
26724962
2016
×
Entrez Id:
643680
Gene Symbol:
MS4A4E
MS4A4E
0.140
GeneticVariation
disease
BEFREE
Our study verified the association between PICALM, BIN1, CLU, and MS4A4E variants and AD susceptibility in Han Chinese populations.
25452228
2016
×
Entrez Id:
643680
Gene Symbol:
MS4A4E
MS4A4E
0.140
GeneticVariation
disease
GWASDB
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
21460841
2011