| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | But, other sites of HLA-A/B/DRB1 in our study had no correlations with AA (all P<sub>c</sub> > 0.05). | 28902578 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Association of Human Leukocyte Antigen DRB1*15 and DRB1*15:01 Polymorphisms with Response to Immunosuppressive Therapy in Patients with Aplastic Anemia: A Meta-Analysis. | 27611583 | 2016 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | HLA-B*51:01, DRB1*03:01 and DRB1*11:01 are expressed at low levels in children with AA. | 22572536 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our results showed a positive association of the DRB1(∗)15 allele in Mexican patients with aplastic anemia, which coincides with that reported internationally. | 22580214 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Although DRB1*03 percent frequency was significantly higher in controls 0.175 (p = 0.023) with odds ratio = 0.514, as compared to patients 0.106.Therefore DRB1*15 emerged as a susceptible allele and DRB1*03 as a protective allele in Pakistani Aplastic anemia patients and control samples. | 19860590 | 2009 | ||||
|
0.080 | Biomarker | disease | BEFREE | In Koreans, DRB1*1501 was associated with disease susceptibility to AA and DRB1*1302 with protection against the severe form of the disease. | 18571007 | 2008 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | To determine whether this DRB1 allele can also predict a response to antithymocyte globulin (ATG) therapy in AA patients, we analysed the results of HLA-DRB1 typing in 59 Japanese patients who received ATG within 2 years after diagnosis of AA and also in 52 patients treated with CyA. | 8562389 | 1996 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | These findings indicate that the CyA-dependent response of AA is closely related to an HLA class II haplotype of DRB1*1501-DQA1*0102-DQB1*0602 and suggest that, in AA patients with this haplotype, immune mechanisms play an important role in the pathogenesis of bone marrow failure. | 7994040 | 1994 |