In addition, recurring mutations in BCOR/BCORL, PIGA, DNMT3A, and ASXL1 as well as cytogenetic abnormalities, namely monosomy 7, trisomy 8, and uniparental disomy of the 6p arm seem to be intimately related to AA pathogenesis.
A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3<sup>-</sup>CD16/CD56<sup>+</sup>NK cells, CD3<sup>+</sup>CD57<sup>+</sup>T-LGL cells and CD19<sup>+</sup>B lymphocytes were detected by flow cytometry.