| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India. | 23869056 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | MTHFR C677T and FVL G1691A polymorphisms may be risk factors for increased vascular complications in patient with SCD. | 23992124 | 2013 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Association between apolipoprotein ε4 allele, factor V Leiden, and plasma lipid and lipoprotein levels with sickle cell disease in Southern Iran. | 20373031 | 2011 | ||||
|
0.080 | Biomarker | disease | LHGDN | Adjusted logistic regression analysis for the effects of age and sex was performed and a significant association was found between factor V Leiden mutation and sickle cell anemia with odds ratios (OR) of 6.5 (95% confidence intervals [CI] 1.19-35.33, P=0.03) in SS patients. | 17619828 | 2008 | ||||
|
0.080 | Biomarker | disease | BEFREE | Thrombophilic mutations among Southern Iranian patients with sickle cell disease: high prevalence of factor V Leiden. | 17619828 | 2008 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The prevalences of factor V Leiden (P = 0.174) and PRT G20210A (P = 0.397) were not different between patients and controls, thereby giving no support to an association of either single-point mutation with SCD. | 15224376 | 2004 | ||||
|
0.080 | Biomarker | disease | BEFREE | An inherited risk for thrombosis, including mutant thermolabile variant of methylenetetrahydrofolate reductase (MTHFR), factor V Leiden, or prothrombin may be the co-factor(s) for avascular necrosis (AVN) in patients with sickle cell disease. | 11146461 | 2000 | ||||
|
0.080 | Biomarker | disease | BEFREE | Factor V Leiden is not responsible for stroke in patients with sickling disorders and is uncommon in African Americans with sickle cell disease. | 8980255 | 1997 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Polymorphism in exon 10 of the human coagulation factor V gene in a population at risk for sickle cell disease. | 9254858 | 1997 |