Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | AlteredExpression | disease | BEFREE | Vascular function in SCD::Keap1F/F::Tie1-Cre mice was significantly improved, with a 50% decrease in vascular leakage and low expression of the adhesion molecules Vcam1 and P-selectin. | 31015205 | 2019 | ||||
|
0.370 | AlteredExpression | disease | BEFREE | Markers of endothelial activation (soluble thrombomodulin and soluble vascular cell adhesion molecule-1) and inflammation (tumor necrosis factor-alpha) were both significantly elevated in hemoglobin SC patients when compared to controls, being as high as the levels seen in patients with sickle cell anemia. | 25596272 | 2015 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | Association of alpha-thalassemia, TNF-alpha (-308G>A) and VCAM-1 (c.1238G>C) gene polymorphisms with cerebrovascular disease in a newborn cohort of 411 children with sickle cell anemia. | 25175566 | 2015 | ||||
|
0.370 | AlteredExpression | disease | BEFREE | Genetic variation in CD36, HBA, NOS3 and VCAM1 is associated with chronic haemolysis level in sickle cell anaemia: a longitudinal study. | 24168396 | 2014 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | In whole genome and single gene analyses, genetic variation at the vascular cell adhesion molecule-1 (VCAM-1) locus has been associated with inflammatory disease and stroke in sickle cell anaemia. | 24075742 | 2013 | ||||
|
0.370 | AlteredExpression | disease | BEFREE | Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1. | 21264913 | 2011 | ||||
|
0.370 | Biomarker | disease | CTD_human | Plasma zinc levels inversely correlate with vascular cell adhesion molecule-1 concentration in children with sickle cell disease. | 16916123 | 2006 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease. | 12393616 | 2002 |