3 potentially pathogenic variants were identified: c.-77G>A in <i>GATA2</i>, p.Ala343Thr (rs370588269) in <i>GATA4</i>, and p.Pro555Ala (rs146243018) in <i>GATA6</i> Multivariate analyses showed that angina was more frequent in patients carrying sarcomeric and GATA rare variants (55% vs 23.2% in non-carriers of GATA rare variants, OR (95% CI) 7.12 (1.23 to 41.27), p=0.029).