Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.300 Therapeutic group CTD_human Anorectal melanoma: successful treatment by surgical excision and combination chemoimmunotherapy. 12397731 2003
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.300 Therapeutic group CTD_human Successful palliation of stenosing anorectal melanoma by intratumoral injections with natural interferon-beta. 12170190 2002
Entrez Id: 5037
Gene Symbol: PEBP1
PEBP1
0.010 AlteredExpression group BEFREE Loss of Raf kinase inhibitor protein expression is associated with human papillomavirus 16 infection in anal tumors. 30008866 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.010 GeneticVariation group BEFREE Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors. 27573925 2016
Entrez Id: 55506
Gene Symbol: MACROH2A2
MACROH2A2
0.010 Biomarker group BEFREE Loss of histone variant macroH2A2 expression is associated with the progression of anal neoplasm and can be used as a prognostic biomarker for high-grade AIN and SCC. 26658220 2016
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
0.010 GeneticVariation group BEFREE K14E7 and K14E6/E7 transgenic mice developed anal tumors (papillomas, atypias and carcinomas combined) at significantly higher rates (88% and 100%, respectively) than either K14E6 or NTG mice (18% and 19%, respectively). 21999991 2011
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
0.010 AlteredExpression group LHGDN FHIT oncosuppressor gene expression profile in human anal cancers. 17393360 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.010 AlteredExpression group LHGDN Proliferation and p53 expression in anal cancer precursor lesions. 12926152 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.010 Biomarker group BEFREE None of the anal tumors showed cyclin D1 amplification. 9042789 1997