Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.320 Biomarker disease BEFREE TGF-β effectors such as SMAD3 were excluded from binding SM22α-encoding chromatin (TAGLN) in TAA samples, while treatment with the EZH2 inhibitor GSK343 improved cytoskeletal architecture and restored SM22α expression. 29515022 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.320 Biomarker disease BEFREE The coding regions of five clinically actionable genes associated with scoliosis (COL3A1, FBN1, TGFBR1, TGFBR2, and SMAD3) and aortic aneurysm were sequenced in 343 adolescent idiopathic scoliosis cases. 26333736 2015
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.320 Biomarker disease CTD_human Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. 21217753 2011