Gene: ACE ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE The rs5516 G allele of KLK1 was significantly associated with AA (P < 0.001), and the D allele of ACE was significantly associated with both AA (P < 0.001) and AS (P < 0.001). 27858843 2016
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE A meta-analysis was conducted on the associations between the ACE I/D polymorphism and all AAs and abdominal aortic aneurysms (AAAs). 23587545 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE However, ACE I/D polymorphism was not associated with thoracic AA risk (OR=1.33; 95%CI, 0.85-2.07; p=0.21; I(2)=52%). 25155622 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE This meta-analysis showed a significant association between ACE I/D polymorphism and aortic aneurysm risk (OR = 1.53, 95% CI 1.26-1.87, P <0.01). 25080510 2014
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE In TAV cases, the D angiotensin-converting enzyme and +896A Toll-like receptor-4 alleles seem to be the predictive factors for TAA risk. 23248206 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE A synergistic effect between the ACE D allele and hypertension was found for both an increased aortic diameter (P=.003) and the risk of TAA (P<.001). 22245237 2012
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.070 GeneticVariation disease BEFREE A polymorphism in the angiotensin-converting-enzyme gene (ACE I/D) has been associated with abdominal aortic aneurysm and a link between aortic aneurysm and aortic stiffness has been suggested. 21570325 2011