Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.330 Biomarker disease BEFREE Lysyl oxidase is shown to protect against AA formation. 31554420 2019
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.330 Biomarker disease BEFREE To achieve this, we use a combination of balloon angioplasty, elastase and collagenase, and a lysyl oxidase inhibitor, called β-aminopropionitrile (BAPN), to create clinically significant infrarenal aortic aneurysms, analogous to human disease. 31814612 2019
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.330 Biomarker disease GENOMICS_ENGLAND Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. 27432961 2016
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.330 AlteredExpression disease BEFREE There was a trend toward elevated Lox gene expression and activity and matrix metalloproteinase-2/9 activity for TAV-TAA, BAV-NA, and BAV-TAA specimens. 23764410 2014