Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.500 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.500 Biomarker disease RGD Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems. 19112094 2009
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
0.400 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.400 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
0.400 Biomarker disease HPO
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.400 Biomarker disease HPO
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.330 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.330 Biomarker disease LHGDN Diagnostic and prognostic value of N-terminal pro B-type natriuretic peptide (NT-proBNP) in patients with chronic aortic regurgitation. 18055041 2008
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.330 AlteredExpression disease LHGDN To serially evaluate amino-terminal-pro-BNP (NT-pBNP) serum levels in patients undergoing aortic valve replacement (AVR) for severe chronic aortic regurgitation (AR), blood samples were drawn preoperatively, 15 days postoperatively, at 6- and 12-month follow-up in 25 consecutive patients. 18353850 2008
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.330 AlteredExpression disease BEFREE CNP mRNA levels were 92% lower (P<0.001) in stenotic valves, whereas no significant changes in the expression of ANP and BNP genes were found compared with valves obtained from patients with aortic regurgitation. 17709640 2007
Entrez Id: 2335
Gene Symbol: FN1
FN1
0.310 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.310 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.310 AlteredExpression disease BEFREE CNP mRNA levels were 92% lower (P<0.001) in stenotic valves, whereas no significant changes in the expression of ANP and BNP genes were found compared with valves obtained from patients with aortic regurgitation. 17709640 2007
Entrez Id: 2335
Gene Symbol: FN1
FN1
0.310 Biomarker disease BEFREE In left ventricular biopsies from patients with aortic valve stenosis (AS) and aortic valve regurgitation and from control subjects, we quantitated mRNAs for angiotensin-converting enzyme (ACE), chymase, transforming growth factor-beta1 (TGF-beta1), collagen I, collagen III and fibronectin by reverse-transcription polymerase chain reaction. 11300459 2001
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
0.300 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 11167
Gene Symbol: FSTL1
FSTL1
0.300 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.300 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
0.300 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.300 Biomarker disease CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 Biomarker disease BEFREE IL-4, -5, -13 and -17A were significantly higher, whereas IL-10 was markedly lower in the nasal lavage fluid samples from AR patients, compared with the control subjects. 31739216 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 AlteredExpression disease BEFREE This study tests a hypothesis that TNF enhances histone deacetylase (HDAC)11 expression to inhibit the expression of IL-10 in B cells of AR patients. 30007011 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 AlteredExpression disease BEFREE The expression of miR-19a and IL-10 was significantly negatively correlated with each other in peripheral B cells of AR patients. 28373650 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 AlteredExpression disease BEFREE However, IL-10 was highly expressed in AI lesions and correlated negatively with IL-22 expression. 21148041 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 Biomarker disease BEFREE This study was undertaken to analyse the allergen-induced in vitro mRNA expression of Th1-type effector cytokine IL-18 and regulatory cytokines IL-10 and TGF-beta during SIT in peripheral blood mononuclear cells (PBMC) of allergic rhinitis (AR) patients. 15005735 2004
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.150 Biomarker disease HPO