×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
AlteredExpression
phenotype
BEFREE
Whole blood cholinesterase levels decreased to less than 10% of the original value by 15 min post WoundStat™ treatment and gradually decreased until the onset of apnoea or until euthanasia.
28853336
2018
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
BEFREE
Patients with BChE deficiency are possibly in danger of postanesthetic apnea .
29631548
2018
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
"Characterization of a novel BCHE ""silent"" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium."
25054547
2014
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
"Characterization of a novel BCHE ""silent"" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium."
25054547
2014
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
GeneticVariation
phenotype
BEFREE
Characterization of a novel BCHE "silent" allele: point mutation (p.Val204Asp ) causes loss of activity and prolonged apnea with suxamethonium.
25054547
2014
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy.
21029050
2011
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy.
21029050
2011
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
GeneticVariation
phenotype
BEFREE
Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy.
21029050
2011
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
BEFREE
Like BChE (-/-) humans, the BChE (-/-) mouse responded to succinylcholine with prolonged respiratory arrest .
18056867
2008
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
AlteredExpression
phenotype
BEFREE
We suggest that determination of BChE activity and phenotype by the micro automated method is well suited to pre-operative screening and detection of at-risk of prolonged apnea in persons receiving succinylcholine in the healthy population of western Iran.
17350607
2007
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
We present one case of patient who presented a five hours long apnoea associated with null cholinesterase activity and detection of a butyrylcholinesterase silent variant (Sil-1, 1 for 100,000 persons in population) after sequencing.
15826794
2005
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
We present one case of patient who presented a five hours long apnoea associated with null cholinesterase activity and detection of a butyrylcholinesterase silent variant (Sil-1, 1 for 100,000 persons in population) after sequencing.
15826794
2005
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population.
12881446
2003
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population.
12881446
2003
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
GeneticVariation
phenotype
BEFREE
Between 1999 and 2002, we genotyped 65 patients referred after prolonged post-SC apnea .Five BCHE gene mutations were analyzed.
12881446
2003
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
GeneticVariation
phenotype
BEFREE
People with genetic variants of butyrylcholinesterase can have hours of prolonged apnoea after a normal dose of succinylcholine or mivacurium.
11928765
2002
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Rapid identification of atypical variant of plasma butyrylcholinesterase by PCR.
12392308
2002
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
Rapid identification of atypical variant of plasma butyrylcholinesterase by PCR.
12392308
2002
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
AlteredExpression
phenotype
BEFREE
Decreased activity of plasma cholinesterase is responsible for prolonged apnea during anesthesia using neuromuscular blockers such as suxamethonium and mivacurium.
11749053
2001
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
GeneticVariation
phenotype
BEFREE
The clinically most important variant is atypical (D70G ) BChE because people with this variant have 2 hours of apnea after receiving a dose of succinylcholine that is intended to paralyze muscles for 3-5 minutes.
10794391
2000
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Plasma cholinesterase deficiency in a neonate: a follow-up.
7788839
1995
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
Plasma cholinesterase deficiency in a neonate: a follow-up.
7788839
1995
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years' experience with the Danish Cholinesterase Research Unit.
7793179
1995
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Biomarker
phenotype
CTD_human
Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years' experience with the Danish Cholinesterase Research Unit.
7793179
1995
×
Entrez Id:
590
Gene Symbol:
BCHE
BCHE
0.400
Therapeutic
phenotype
CTD_human
Succinylcholine-induced prolonged apnea in a 3-week-old newborn: treatment with human plasma cholinesterase.
1734774
1992