Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.240 Biomarker disease BEFREE We used a pan-DC, CD11c-specific cre-lox gene knockout mouse model to assess the role of KLF2 in DC activation, function, and control of inflammation in the context of hypercholesterolemia and atherosclerosis. 27837103 2016
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.240 AlteredExpression disease BEFREE Aberrant expression or activation of LOX alters the cellular microenvironment, leading to many diseases, including atherosclerosis, tissue fibrosis, and cancer. 28036074 2016
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.240 Biomarker disease BEFREE This stiffening can be reduced by administration of the lysyl oxidase inhibitor BAPN, and BAPN treatment attenuates atherosclerosis despite highly elevated cholesterol. 23103162 2012
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.240 Biomarker disease BEFREE Pro-resolving and anti-inflammatory mediator products of murine 12/15-lipoxygenase (LOX) exhibit potent actions on vascular inflammation and protect against the progression of atherosclerosis. 21474962 2011
Entrez Id: 4015
Gene Symbol: LOX
LOX
0.240 Biomarker disease RGD Increased lysyl oxidase activity in blood vessels of hypertensive rats and effect of beta-aminopropionitrile on arteriosclerosis. 24127 1977