| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Tolerogenic Dendritic Cells Generated by BAFF Silencing Ameliorate Collagen-Induced Arthritis by Modulating the Th17/Regulatory T Cell Balance. | 31843958 | 2020 | ||||
|
0.090 | Biomarker | disease | BEFREE | In this study, we found that treatment of the collagen-induced arthritis (CIA) mice with CGA significantly attenuated arthritis progression and markedly inhibited BAFF production in serum as well as the production of serum TNF-<i>α</i>. | 31240234 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Paeoniflorin-6'-O-benzene sulfonate alleviates collagen-induced arthritis in mice by downregulating BAFF-TRAF2-NF-κB signaling: comparison with biological agents. | 30446734 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Unlike TACI-Fc, BAFF-Trap bound BAFF but not APRIL (a proliferation-inducing ligand), and significantly suppressed the development of collagen-induced arthritis and adjuvant-induced arthritis. | 31231554 | 2019 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | BAFF levels were higher in adults with arthritis [p = 0.018], weight loss [p = 0.007], and PAH [p = 0.004]. | 29516280 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | BAFF and its receptors involved in the inflammation progress in adjuvant induced arthritis rats. | 26688104 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | Curcumin protects against collagen-induced arthritis via suppression of BAFF production. | 23184090 | 2013 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | All markers of B-cell activation except BAFF and IgM were significantly higher in patients with early RA than those with undifferentiated arthritis. | 19627580 | 2009 | ||||
|
0.090 | Biomarker | disease | BEFREE | Moreover, we revealed a previously unrecognized role for BAFF in promoting the expansion of Th17 cells and demonstrated IL-17 as a crucial effector cytokine for BAFF-mediated proinflammatory effects during collagen-induced arthritis development. | 18820032 | 2008 |