Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE Interestingly, NSC23766 alleviated the process of collagen-induced arthritis of DBA mice in vivo, including the reduced hind paw thickness and ankle stiffness, the reduction of arthritic scores and incidence of arthritis. 30880553 2020
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE Exposure of leukocytes from type II collagen-immunized DBA/1 mice to ibudilast in vitro attenuated their ability to adoptively transfer arthritis to DBA/1J-Prkdc<sup>SCID</sup> mice, providing evidence of an immunomodulatory effect. 30474934 2019
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE Alpha-mangostin: Anti-inflammatory and antioxidant effects on established collagen-induced arthritis in DBA/1J mice. 30557668 2019
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 AlteredExpression disease BEFREE Using a panel of immunohistochemical and immunofluorescence analyses in a CIA model established in 18 DBA/1J mice, we demonstrated that IL-35 promotes synoviocyte apoptosis and alternative activation of macrophages to alleviate arthritis in vivo. 30834683 2019
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE A mouse model of DBA/1JJmsSlc collagen-induced arthritis was treated with Th2 or Th17 cell inhibitor, and transepidermal water loss (TEWL) and the expression of markers associated with allergic reaction and inflammation were evaluated. 30828078 2019
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE Exogenous GH administration in arthritic DBA/1J mice reduced the severity of established CIA as well as the inflammatory environment, which also shows a GH effect on arthritis progression. 29887869 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE Mice with DBA/1JJmsSlc collagen-induced arthritis were treated with inhibitors or neutralizing antibodies. 29698950 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 AlteredExpression disease BEFREE The results showed that LCA significantly suppressed arthritis via the activation of SQSTM1 (p62)/nuclear factor-erythroid 2-related factor 2 (Nrf2) signaling in the collagen-induced arthritis (CIA) model of DBA mice. 29233793 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE DBA/1JJmsSlc control mice (n = 5) and DBA/1JJmsSlc collagen-induced arthritis mouse model (arthritis mice; n = 5) were used. 28573874 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE In this study, we investigated the improvement of astilbin and low-dose MTX combination on collagen-induced arthritis in DBA/1J mice. 29410374 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE DBA/1J mice with CIA that received IL-17-/- donor bone marrow showed potently inhibited development and severity of clinical arthritis as compared with CIA mice that received WT bone marrow. 23114425 2012
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 GeneticVariation disease BEFREE CIA was induced in DBA/1J mice.Arthritic mice were treated with bosentan (100 mg/kg) once a day, starting from the day when arthritis was clinically detectable. 22249931 2012
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE In contrast to the situation in humans, lpxL1 LPS has agonistic activity for cytokine production in peritoneal macrophages of DBA mice, and exacerbated arthritis in murine collagen induced arthritis model. 21088052 2011
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis. 18178865 2008
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE To induce arthritis in mice, rYKL-39 (1, 10 or 50 g in Freund's incomplete adjuvant) was injected into the right footpad of mice from four different strains (BALB/c, DBA/1J, C57BL/6 and ICR). 12102470 2003
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 GeneticVariation disease BEFREE Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice. 10051620 1999
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.100 Biomarker disease BEFREE To find an "unlimited" source of antigenic material (aggrecan) for arthritis induction in BALB/c mice; to analyze the specificities of immune reactions to aggrecan and type II collagen in 2 arthritis-susceptible murine strains, BALB/c mice for proteoglycan (aggrecan)-induced arthritis and DBA/1j mice for collagen-induced arthritis; to compare the histopathologic features of arthritis induced by purified aggrecans or total extracts of osteoarthritic (OA) cartilage; and to determine arthritis susceptibility in various BALB/c colonies. 9627010 1998