Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
0.700 Biomarker disease HPO
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
0.700 Biomarker disease CTD_human
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
0.700 Biomarker disease HPO
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
0.500 CausalMutation disease CLINVAR
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
0.500 Biomarker disease HPO
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.500 Biomarker disease HPO
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
0.500 GeneticVariation disease CLINVAR
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
0.500 SusceptibilityMutation disease CLINVAR
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
0.500 Biomarker disease HPO
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
0.500 Biomarker disease CTD_human
Entrez Id: 4795
Gene Symbol: NFKBIL1
NFKBIL1
0.470 Biomarker disease HPO
Entrez Id: 4795
Gene Symbol: NFKBIL1
NFKBIL1
0.470 Biomarker disease CTD_human
Entrez Id: 51744
Gene Symbol: CD244
CD244
0.440 SusceptibilityMutation disease CLINVAR
Entrez Id: 51744
Gene Symbol: CD244
CD244
0.440 Biomarker disease HPO
Entrez Id: 1777
Gene Symbol: DNASE2
DNASE2
0.230 Biomarker disease MGD
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
0.110 CausalMutation disease CLINVAR
Entrez Id: 55578
Gene Symbol: SUPT20H
SUPT20H
0.110 SusceptibilityMutation disease CLINVAR
Entrez Id: 2643
Gene Symbol: GCH1
GCH1
0.100 Biomarker disease HPO
Entrez Id: 6902
Gene Symbol: TBCA
TBCA
0.020 Biomarker disease BEFREE <b>:</b> To study new target-oriented molecules that are active against rheumatoid arthritis-dependent pain, new dual inhibitors incorporating both a carbonic anhydrase (CA)-binding moiety and a cyclooxygenase inhibitor (NSAID) were tested in a rat model of rheumatoid arthritis induced by CFA intra-articular (i.a.) injection. 31003542 2019
Entrez Id: 706
Gene Symbol: TSPO
TSPO
0.050 Biomarker disease BEFREE <b>Abbreviations:</b> 3-MA: 3-methyladenine; ACPA: anti-citrullinated peptide antibodies; anti-CCP: anti-cyclic citrullinated peptide antibody; cVIM: citrullinated VIM; BECN1: beclin1; DAPI: 4',6-diamidino-2-phenylindole; FBS: fetal bovine serum; HLA: human leukocyte antigen; IFNG/IFN-γ: interferon gamma; IL6: interleukin 6; IP: immunoprecipitation; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence index; MHC: major histocompatibility complex; OA: osteoarthritis; PADI: peptidyl arginine deiminase; PepA: pepstatin A; PBS: phosphate-buffered saline; PtdIns3K: phosphatidylinositol 3-kinase; RA: rheumatoid arthritis; SFs: synovial fibroblasts; siRNA: small interfering RNA; VIM: vimentin. 31486697 2020
Entrez Id: 1131
Gene Symbol: CHRM3
CHRM3
0.010 Biomarker disease BEFREE <b>Abbreviations:</b> 3-MA: 3-methyladenine; ACPA: anti-citrullinated peptide antibodies; anti-CCP: anti-cyclic citrullinated peptide antibody; cVIM: citrullinated VIM; BECN1: beclin1; DAPI: 4',6-diamidino-2-phenylindole; FBS: fetal bovine serum; HLA: human leukocyte antigen; IFNG/IFN-γ: interferon gamma; IL6: interleukin 6; IP: immunoprecipitation; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence index; MHC: major histocompatibility complex; OA: osteoarthritis; PADI: peptidyl arginine deiminase; PepA: pepstatin A; PBS: phosphate-buffered saline; PtdIns3K: phosphatidylinositol 3-kinase; RA: rheumatoid arthritis; SFs: synovial fibroblasts; siRNA: small interfering RNA; VIM: vimentin. 31486697 2020
Entrez Id: 5132
Gene Symbol: PDC
PDC
0.020 Biomarker disease BEFREE <b>Abbreviations:</b> AA: Alopecia areata; AIRE: Autoimmune Regulator; APECED: Autoimmune, Polyendocrinopathy Candidiasis Ectodermal Dystrophy; DLQI: Dermatology life quality index questionnaire; MIQE: Minimum information for publication of quantitative real-time PCR experiments; mTEC: Medullary thymic epithelial cells; PHD: Plant homeodomain; qRT-PCR: Quantitative reversetranscription-polymerase chain reaction; RA: Rheumatoid arthritis. 31601134 2020
Entrez Id: 1055
Gene Symbol: CECR
CECR
0.010 GeneticVariation disease BEFREE <b>Aim:</b> To study if cumulative glucocorticoid use could be related to cognitive impairment in rheumatoid arthritis (RA) patients.<b>Methods:</b> A sample of 60 RA patients and 64 controls were studied for the Mini Mental State Examination (MMSE) and depression scale (using CES-D or Center for Epidemiological Studies Depression scale). 31625439 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.700 Biomarker disease BEFREE <b>Conclusion</b>: TNFα antagonists are used less often and glucocorticoids more often in elderly patients with active RA compared to their younger counterparts. 30230962 2018
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
0.500 Biomarker disease BEFREE <b>Conclusion</b>: Serum capacity to activate PAD4 was associated with ACPA and RF positivity and earlier disease onset in early RA patients, and decreased after initiation of DMARD treatment, indicating that anti-PAD treatment could potentially be beneficial in RA. 31544586 2020