Gene: PIK3CB ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.100 AlteredExpression disease BEFREE Activation of PI3K/Akt signaling pathway exists in TNF-α-induced production of IL-1β and MMP3 on RA FLS, which is hampered by PI3K inhibitor LY294002. 23328930 2013
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.100 Biomarker disease BEFREE This novel observation provides the scope to develop new therapeutics targeting PI3K/Akt/mTOR signaling pathway in autoimmune diseases like psoriasis and rheumatoid arthritis. 22840496 2012
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.100 AlteredExpression disease BEFREE We found that IL-17 induction of CCL2/MCP-1 was mediated by the PI3K, ERK, and JNK pathways in RA ST fibroblasts and by the PI3K and ERK pathways in macrophages. 20228199 2010
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.100 Biomarker disease BEFREE In the present study, we investigated the role of the phosphoinositide 3-kinase (PI3K)/Akt pathway in the regulation of IL-17 production in RA. 15642134 2005