Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom. 20401725 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE As a result of our study, angiotensin converting enzyme gene I/D polymorphism DD genotype could be a genetic marker in rheumatoid arthritis in the Turkish study population. 23000565 2012
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 Biomarker disease BEFREE Primary prevention of myocardial infarction with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in hypertensive patients with rheumatoid arthritis-A nationwide cohort study. 29216228 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our study suggests that high frequency of the ACE D allele contributes to the heritability of RA susceptibility compared to other ACE alleles. 23981749 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our meta-analysis demonstrates that the ACE I/D polymorphism is associated with susceptibility to RA, especially in Arab populations. 23413281 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.090 GeneticVariation disease BEFREE Our study found an association between ACE deletion polymorphism and RA. 17985406 2007
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.330 Biomarker disease BEFREE G-protein-coupled receptor kinases (GRKs) are implicated in the pathophysiology of human diseases such as arterial hypertension, heart failure and rheumatoid arthritis. 15225142 2004
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.330 AlteredExpression disease BEFREE Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. 10094932 1999
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.330 AlteredExpression disease BEFREE CXCR7 was expressed on endothelial cells in RA synovium and also on unstimulated HUVECs. 20617529 2010
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.330 Biomarker disease CTD_human Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. 19192274 2009
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7
0.030 Biomarker disease BEFREE Efficacy of tocilizumab monotherapy after response to combined tocilizumab and methotrexate in patients with rheumatoid arthritis: the randomised JUST-ACT study. 30299241 2019
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7
0.030 GeneticVariation disease BEFREE Correlation of fatigue with other disease related and psychosocial factors in patients with rheumatoid arthritis treated with tocilizumab: ACT-AXIS study. 31261500 2019
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7
0.030 GeneticVariation disease BEFREE Median time to low disease activity is shorter in tocilizumab combination therapy with csDMARDs as compared to tocilizumab monotherapy in patients with active rheumatoid arthritis and inadequate responses to csDMARDs and/or TNF inhibitors: sub-analysis of the Swiss and Austrian patients from the ACT-SURE study. 28776300 2017
Entrez Id: 55289
Gene Symbol: ACOXL
ACOXL
0.100 GeneticVariation disease GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
Entrez Id: 55289
Gene Symbol: ACOXL
ACOXL
0.100 GeneticVariation disease GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
Entrez Id: 52
Gene Symbol: ACP1
ACP1
0.010 GeneticVariation disease BEFREE Likewise, the ACP1*C allele showed evidence of association with CV events in patients with RA (P = 0.024, OR = 2.43). 21767392 2011
Entrez Id: 54
Gene Symbol: ACP5
ACP5
0.030 Biomarker disease LHGDN Serum tartrate-resistant acid phosphatase isoforms in rheumatoid arthritis. 11983200 2002
Entrez Id: 54
Gene Symbol: ACP5
ACP5
0.030 Biomarker disease LHGDN Significance of serum TRACP in rheumatoid arthritis. 18410226 2008
Entrez Id: 54
Gene Symbol: ACP5
ACP5
0.030 Biomarker disease BEFREE Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio. 28792533 2017
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 Biomarker disease BEFREE Patients included in the early arthritis ESPOIR cohort who fulfilled the ACR-EULAR (American College of Rheumatology/European League against Rheumatism) criteria for RA and received MTX as a first DMARD were assessed. 28866645 2017
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 Biomarker disease BEFREE 17 patients with active disease matching the ACR/EULAR 2010 criteria for RA were included. 30944956 2019
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 Biomarker disease BEFREE Patients with RA satisfying ACR criteria were included and peripheral blood obtained for lymphoproliferative assay, antibody level and HLA typing. 23543349 2013
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 Biomarker disease BEFREE All 20 enrolled patients met 2010 ACR/EULAR criteria for RA and were classified into good, moderate and non-responders (GR, MR, NR) for triple therapy. 31146113 2019
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 GeneticVariation disease BEFREE Four hundred and twelve patients with RA (ACR 1987) and 215 controls were included. 21952999 2012
Entrez Id: 49
Gene Symbol: ACR
ACR
0.100 GeneticVariation disease BEFREE A total of 156 patients with RA according to the ACR criteria, and 200 control subjects were recruited into the study. 23773307 2014