Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASCAT Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis. 26546613 2016
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676 2015
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASCAT Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. 24782177 2014
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASDB Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. 24782177 2014
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 Biomarker disease BEFREE Combined longitudinal analysis of the 2 cohorts suggests further association of several loci with Larsen score (KIF5A, PTPN22, AFF3, TAGAP) and therefore a significant accumulation of RA severity markers among RA susceptibility markers (p = 0.016). 23242182 2013
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 Biomarker disease CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease BEFREE By targeting a variant with convincing evidence for association with rheumatoid arthritis, significant association of AFF3 rs10865035 with SLE was detected in the Chinese population, indicating that AFF3 might be a common autoimmunity gene. 22983539 2012
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease BEFREE Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis. 20498205 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease GWASCAT Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 Biomarker disease CTD_human Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease BEFREE There is less overlap reported with rheumatoid arthritis (RA) than PsV susceptibility loci but one report suggests that the AFF3 locus may be associated with both RA and PsA. 20084005 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease BEFREE Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment. 20444755 2010
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
0.460 GeneticVariation disease BEFREE A novel RA susceptibility locus at AFF3 was identified with convincing evidence for association in a combined sample cohort of 6819 RA cases and 12 650 controls [OR 1.12 95% confidence intervals (CI) 1.07-1.17, P = 2.8 x 10(-7)]. 19359276 2009