Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE A novel long non-coding RNA in the rheumatoid arthritis risk locus TRAF1-C5 influences C5 mRNA levels. 26673966 2016
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 Biomarker disease BEFREE A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis. 25566937 2015
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 Biomarker disease BEFREE We found that TRAF1/C5 risk RA variants potentially influence anti-TNF treatment response. 25834819 2015
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Associations between TRAF1-C5 gene polymorphisms and rheumatoid arthritis: a meta-analysis. 24144456 2014
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE A single nucleotide polymorphism of TRAF1 predicts the clinical response to anti-TNF treatment in Japanese patients with rheumatoid arthritis. 24321457 2014
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Association between polymorphism in TRAF1/C5 gene and risk of rheumatoid arthritis: a meta-analysis. 24234752 2014
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Association study of TRAF1/C5 polymorphism (rs10818488) with susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis. 23321589 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE This represents the second independent study correlating rs2900180 at the TRAF1 locus with radiological severity in RA. 23242182 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Sixty-three RA patients were included.Nine genes (13 SNPs) were subsequently analyzed, including those coding for cytokines involved in synovitis (IL10, LTA, TGFβ1, TNF-α, TNF receptor II) and genes associated with RA susceptibility (-C5 TRAF1, STAT4, TNFAIP3 and PTPN22). 22129793 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 Biomarker disease CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE To assess the frequency of the RA-conferring susceptibility TRAF1 polymorphisms rs3761847 and rs2900180 in a cohort of PBC patients. 23125866 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2013
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population. 22196377 2012
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE We also demonstrate that in the presence of SE, the minor allele of MMEL1-TNFRSF14 significantly reduces RA risk in a dominant manner, whereas TRAF1-C5 increases the risk. 21614018 2012
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population. 21492465 2011
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Our results are in keeping with a previous report and suggest that the TRAF1/C5 region is associated with risk of development of radiological erosions in IP/RA patients. 20219786 2011
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese. 19336421 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE The TRAF1/C5 locus in particular warrants further investigation in RA as a potential disease severity locus. 20353580 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 Biomarker disease BEFREE In particular, recent discoveries highlight the importance of the CD40/NF-kappaB signaling pathway in RA, based on genetic association with several genes relevant to this pathway, including CD40, TRAF1, TNFAIP3, and REL. 20192992 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies. 20205706 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 Biomarker disease BEFREE A novel association with a 100-kb region on chromosome 9 that contains the tumor necrosis factor receptor-associated factor 1 (TRAF1) and C5 genes has been observed in some autoimmune rheumatic diseases, in particular in rheumatoid arthritis. 19918040 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis. 20498205 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease BEFREE Lack of association of PTPN22, STAT4 and TRAF1/C5 gene polymorphisms with cardiovascular risk in rheumatoid arthritis. 20822712 2010
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
0.500 GeneticVariation disease GWASCAT Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842 2010