| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Pingchuanning decoction attenuates airway inflammation by suppressing autophagy via phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway in rat models of asthma. | 30260006 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Secreted Hsp90α medicates HDM-induced asthmatic airway epithelial barrier dysfunction via PI3K/AKT pathway, indicating that anti-secreted Hsp90α therapy might be a potential treatment to asthma in future. | 31747880 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | These findings indicate that DK-1014 can protect against allergic airway inflammation through the AP-1 and AKT/mTOR pathways and could be useful source for the development of a therapeutic agent for asthma. | 30696844 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we described the role of miRNA-133a in asthma and demonstrated it in regulating airway remodeling of asthma through the phosphoinositide 3 kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway by targeting IGF-1 receptor (IGF1R). | 30146725 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | The PI3K-AKT pathway is known to regulate cytokines in dust mite-induced pediatric asthma. | 30406061 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma. | 29207033 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we revealed that OX40L could regulate differentiation of helper T cells via PI3K/AKT and p38 MAPK signaling pathway in asthma. | 29554934 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | LAT-PLC-γ1 interaction may contribute to LAT activity in vivo and LAT protects against asthma partly via Raf-MEK-ERK and PI3K-AKT-CREB pathways. | 28063403 | 2017 |