Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASCAT Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. 30787307 2019
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 Biomarker disease BEFREE To investigate whether the genetic variants of TGFB1, TLE4, MUC22 and IKZF3 are associated with the development of asthma in Chinese children. 28262390 2018
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease BEFREE Chromosomal region 17q12-q21 is associated with asthma and harbors regulatory polymorphisms that influence expression levels of all five protein-coding genes in the region: IKAROS family zinc finger 3 (Aiolos) (IKZF3), zona pellucida binding protein 2 (ZPBP2), ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3), and gasdermins A and B (GSDMA, GSDMB). 28241063 2017
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASCAT A meta-analysis of genome-wide association studies of asthma in Puerto Ricans. 28461288 2017
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease BEFREE In the Swedish Search study, we found significant differences in DNA methylation between asthmatics and controls in five CpG sites; after adjusting for lymphocyte and neutrophil cell counts, three remained significant: one in IKZF3 [IKAROS family zinc finger 3 (Aiolos); cg16293631] and two in the CpG island (CGI) of ORMDL3 (cg02305874 and cg16638648). 25256354 2015
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 Biomarker disease CTD_human In the Swedish Search study, we found significant differences in DNA methylation between asthmatics and controls in five CpG sites; after adjusting for lymphocyte and neutrophil cell counts, three remained significant: one in IKZF3 [IKAROS family zinc finger 3 (Aiolos); cg16293631] and two in the CpG island (CGI) of ORMDL3 (cg02305874 and cg16638648). 25256354 2015
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASDB Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. 24406073 2014
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease BEFREE We confirmed the strong allelic association between SNPs in the 17q21 region and asthma in Latinos (IKZF3, lowest P value: rs90792, odds ratio, 0.67; 95% CI, 0.61-0.75; P = 6 × 10(-13)) and replicated associations in several genes that had previously been associated with asthma in genome-wide association studies. 24406073 2014
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease BEFREE We found 2 SNPs (1 novel rs9635726 in IKZF3) to be associated with asthma. 23622005 2013
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease BEFREE Sixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559). 22626592 2012
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.460 GeneticVariation disease GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503 2010