Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 Biomarker disease BEFREE SIRT1 activator E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression. 29787963 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 AlteredExpression disease BEFREE Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. 18689793 2008
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 AlteredExpression disease BEFREE SIRT1 was demonstrated to be a direct target of miR‑217 and was downregulated in atherosclerosis. 31432137 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 AlteredExpression disease BEFREE The present study indicated that miR‑92a prevented the migration of H2O2‑induced VSMCs by repressing the expression of SIRT1, and also provided a novel therapy to protect against the phenotypic change of VSMCs in atherosclerosis. 29115493 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 AlteredExpression disease LHGDN Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. 18689793 2008
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 AlteredExpression disease BEFREE Decreased expression of SIRT1 in artery may be involved in the initiation and development of diabetic atherosclerosis. 21810449 2011