Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE The haptoglobin 2-2 genotype is associated with lower haptoglobin concentrations and atherosclerosis in diabetes. 28830235 2017
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE The haptoglobin 2-2 genotype is associated with atherosclerosis in type 2 diabetes mellitus. 27190085 2016
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 AlteredExpression disease BEFREE Zonulin reversibly modulate intestinal permeability (IP), the circulating zonulin levels were increased in diabetes, obesity, all of which are risk factors for atherosclerosis. 27353603 2016
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Biomarker disease BEFREE Haptoglobin (Hb) and adiponectin are antioxidant proteins and independent predictors of atherosclerotic vascular disease in diabetic patients. 23177015 2013
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Therapeutic disease RGD Vasoprotective effect of vitamin E: rescue of ethanol-induced atherosclerosis and inflammatory stress in rat vascular wall. 23665315 2013
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis. 22766337 2012
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE We hypothesized that the Hp genotype would predict progression of coronary artery calcification (CAC), a marker of subclinical atherosclerosis. 22098782 2011
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Biomarker disease BEFREE Beyond the conventional view of haptoglobin as a marker of hemolysis, several findings point towards an immunomodulatory effect of haptoglobin in B-cell mediated progression of atherosclerosis. 21507405 2011
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Biomarker disease BEFREE Haptoglobin (Hp) is an antioxidant protein and the major susceptibility gene for atherosclerosis in diabetic patients. 18082523 2007
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE These findings should foster research investigating the role of Hp polymorphism in human disease, and in vitamin C deficiency and atherosclerosis in particular. 17644791 2007
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Biomarker disease CTD_human Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on host-pathogen interactions in tuberculosis and HIV. 16597321 2006
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 AlteredExpression disease BEFREE Serum haptoglobin levels are associated with non-transplant atherosclerosis. 14734126 2004
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE The Hp polymorphism is related to the prevalence and the outcome of various pathological conditions with altered iron metabolism such as hemochromatosis, infections, and atherosclerotic vascular disease. 12005209 2002
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 GeneticVariation disease BEFREE Variation at the haptoglobin locus could have a direct effect on the degradation of elastin in atherosclerotic aorta, whereas variation at the cholesterol ester transfer protein locus could affect lipid metabolism and promote atherosclerosis.(ABSTRACT TRUNCATED AT 250 WORDS) 1967566 1990