Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease BEFREE Genetic model analysis shown that the minor allele T of GJA5 rs35594137 was associated with a decreased AF risk under the recessive model (OR = 0.40; 95% CI: 0.19-0.86; p = 0.018) and the minor allele G of KCNJ2 rs8079702 was associated with an increased AF risk in the recessive model (OR = 2.31; 95% CI: 1.20-4.42; p = 0.012). 31270966 2019
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 Biomarker disease BEFREE In conclusion, this study provides mechanistic insights into atrial proarrhythmia with SQT3 Kir2.1 mutations and highlights possible pharmacological strategies for management of SQT3-linked AF. 28609477 2017
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 Biomarker disease GENOMICS_ENGLAND Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1. 25691870 2015
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease BEFREE Using a linear regression model and adapting a resampling inference, a decrease in longitudinal QTc variance was found to associate with SNPs near KCNH2 (rs10240738) and KCNJ2 (rs8079702) when adjusted for patient age, gender, AF type, and average QTc. 24460807 2014
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease BEFREE KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia. 23440193 2013
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease BEFREE The aim of this study was to screen lone atrial fibrillation (AF) patients for mutations in the genes KCNJ2, KCNJ3 and KCNJ5, all encoding potassium channels. 21555883 2011
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease BEFREE We sought to determine if mutations in KCNJ2 and KCNE1-5 are a common cause of atrial fibrillation. 16887036 2006
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 Biomarker disease BEFREE Recently, strong evidences showed that Kir2.1 channels were associated with mouse atrial fibrillation (AF), therefore we hypothesized that KCNJ2 was associated with familial AF. 15922306 2005
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 GeneticVariation disease LHGDN Thirty Chinese AF kindreds were evaluated for mutations in KCNJ2 gene. 15922306 2005
Entrez Id: 3759
Gene Symbol: KCNJ2
KCNJ2
0.470 Biomarker disease HPO