Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 18
Gene Symbol: ABAT
ABAT
0.310 Biomarker disease CTD_human Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: evidence of association at GRIN2A and ABAT. 15830322 2005
Entrez Id: 36
Gene Symbol: ACADSB
ACADSB
0.300 Biomarker disease CTD_human 2-methylbutyryl-CoA dehydrogenase deficiency associated with autism and mental retardation: a case report. 17883863 2007
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.310 Biomarker disease CTD_human There were strong associations between both DD genotype of ACE I/D and the D allele, with autism (P = 0.006, OR = 2.9, 95% CI = 1.64-5.13 and P = 0.006, OR = 2.18, 95% CI = 1.37-3.48 respectively). 27082637 2016
Entrez Id: 100
Gene Symbol: ADA
ADA
0.340 Biomarker disease CTD_human We suggest that this putative genotype-dependent reduction in ADA activity may be a risk factor for the development of autism. 11354825 2001
Entrez Id: 133
Gene Symbol: ADM
ADM
0.300 Biomarker disease CTD_human The mean values of plasma total nitrite and AM levels in the autistic group were significantly higher than control values, respectively (p < 0.001, p = 0.028). 12579522 2003
Entrez Id: 23394
Gene Symbol: ADNP
ADNP
0.500 Biomarker disease CTD_human A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP. 24531329 2014
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
0.310 Biomarker disease CTD_human The objective of this study was to determine whether alleles in ADRB2 are associated with diagnosis of autism in the Autism Genetic Resource Exchange (AGRE) population. 17199132 2007
Entrez Id: 158
Gene Symbol: ADSL
ADSL
0.430 Biomarker disease CTD_human An Australian patient with autism was found to be heterozygous for two mutations in the gene encoding adenylosuccinate lyase (ASL), resulting in the protein mutations E80D and D87E. 15471876 2004
Entrez Id: 116987
Gene Symbol: AGAP1
AGAP1
0.320 Biomarker disease CTD_human We therefore assessed CENTG2 for its involvement in autism by (1) screening its exons for variants in 199 autistic and 160 non-autistic individuals, and (2) genotyping and assessing intra-genic polymorphisms for linkage and linkage disequilibrium (LD). 15892143 2005
Entrez Id: 26523
Gene Symbol: AGO1
AGO1
0.300 Biomarker disease GENOMICS_ENGLAND Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder. 29346770 2018
Entrez Id: 54806
Gene Symbol: AHI1
AHI1
0.340 Biomarker disease CTD_human Re-sequencing was first used to screen AHI1, followed by two subsequent association studies, one limited and one covering the gene more completely, in Autism Genetic Resource Exchange (AGRE) families. 18782849 2008
Entrez Id: 324
Gene Symbol: APC
APC
0.310 Biomarker disease CTD_human Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion. 8071957 1994
Entrez Id: 324
Gene Symbol: APC
APC
0.310 Biomarker disease CTD_human Association of adenomatous polyposis coli (APC) gene polymorphisms with autism spectrum disorder (ASD). 17221838 2007
Entrez Id: 361
Gene Symbol: AQP4
AQP4
0.310 Biomarker disease CTD_human These data suggest that changes are apparent in markers for abnormal glial-neuronal communication (connexin 43 and aquaporin 4) in brains of subjects with autism. 18435417 2008
Entrez Id: 367
Gene Symbol: AR
AR
0.340 Biomarker disease CTD_human The results lend some support for an influence of the studied polymorphisms on the susceptibility for autism, but argue against the possibility that mutations in the AR gene are common in subjects with this condition. 19167832 2009
Entrez Id: 40
Gene Symbol: ASIC2
ASIC2
0.310 Biomarker disease CTD_human Nominally significant single SNP and/or haplotype-based association results were detected in 15 genes, of which, MYO1D, ACCN1 and LASP1 stand out as genes with autism risk alleles requiring further study, with potential GRRs in the range of 1.34-2.29. 17376794 2007
Entrez Id: 438
Gene Symbol: ASMT
ASMT
0.340 Biomarker disease CTD_human Abnormal melatonin synthesis in autism spectrum disorders. 17505466 2008
Entrez Id: 23245
Gene Symbol: ASTN2
ASTN2
0.300 Biomarker disease CTD_human Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 19404257 2009
Entrez Id: 57194
Gene Symbol: ATP10A
ATP10A
0.340 Biomarker disease CTD_human Dense linkage disequilibrium mapping in the 15q11-q13 maternal expression domain yields evidence for association in autism. 12851639 2003
Entrez Id: 551
Gene Symbol: AVP
AVP
0.400 Biomarker disease CTD_human Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study. 8570775 1995
Entrez Id: 552
Gene Symbol: AVPR1A
AVPR1A
0.390 Biomarker disease CTD_human We tested for association between the AVPR1a microsatellites and autism in 116 families (128 probands diagnosed with the ADI-R and ADOS-G using a family-based association test (UNPHASED)). 16520824 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.330 Biomarker disease CTD_human Immunohistochemical analyses of tissue arrays containing slices of the cerebellum and frontal cortex of autistic and age- and sex-matched control subjects revealed decreased expression of RORA and BCL-2 proteins in the autistic brain. 20375269 2010
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.330 Biomarker disease CTD_human Quantification of Bcl-2 levels showed a 34% to 51% reduction in autistic cerebellum (M +/- SD per 75 microg protein 0.29 +/- 0.08; N = 5) compared with controls (M +/- SD per 75 microg protein 0.59 +/- 0.31; N = 8, p < 0.0451). 11814262 2001
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease CTD_human We suggest that BDNF has a possible role in the pathogenesis of autism through its neurotrophic effects on the serotonergic system. 17349978 2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease CTD_human By substantiating the previously observed increase in BDNF levels in autistic children in a larger patient set, and suggesting a genetic association between NTRK2 and autism, this study integrates evidence from multiple levels supporting the hypothesis that alterations in BDNF/tyrosine kinase B (TrkB) signaling contribute to an increased vulnerability to autism. 20662941 2010