Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64326
Gene Symbol: COP1
COP1 		0.300 Biomarker disease CTD_human Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 19404257 2009
Entrez Id: 1356
Gene Symbol: CP
CP 		0.310 Biomarker disease CTD_human These results indicate altered regulation of transferrin and ceruloplasmin in autistic children who lose acquired language skills. 15363659 2004
Entrez Id: 7812
Gene Symbol: CSDE1
CSDE1 		0.420 Biomarker disease GENOMICS_ENGLAND Our study defines a new autism-related syndrome and highlights the functional role of CSDE1 in synapse development and synaptic transmission. 31579823 2019
Entrez Id: 114788
Gene Symbol: CSMD3
CSMD3 		0.310 Biomarker disease CTD_human Two patients with balanced translocations and autistic disorder: CSMD3 as a candidate gene for autism found in their common 8q23 breakpoint area. 18270536 2008
Entrez Id: 9820
Gene Symbol: CUL7
CUL7 		0.300 Biomarker disease CTD_human Excess of rare, inherited truncating mutations in autism. 25961944 2015
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		0.310 Biomarker disease CTD_human These results indicate that RORA has the potential to be under both negative and positive feedback regulation by male and female hormones, respectively, through one of its transcriptional targets, aromatase, and further suggest a mechanism for introducing sex bias in autism. 21359227 2011
Entrez Id: 1600
Gene Symbol: DAB1
DAB1 		0.330 Biomarker disease CTD_human Reductions in Reelin protein and mRNA and Dab 1 mRNA and elevations in Reln receptor VLDLR mRNA demonstrate impairments in the Reelin signaling system in autism, accounting for some of the brain structural and cognitive deficits observed in the disorder. 15820235 2005
Entrez Id: 1610
Gene Symbol: DAO
DAO 		0.300 Biomarker disease CTD_human Association of the DAO and DAOA gene polymorphisms with autism spectrum disorders in boys in Korea: a preliminary study. 17629951 2007
Entrez Id: 1717
Gene Symbol: DHCR7
DHCR7 		0.400 Biomarker disease CTD_human Abnormal serotonergic development in a mouse model for the Smith-Lemli-Opitz syndrome: implications for autism. 14659996 2003
Entrez Id: 1719
Gene Symbol: DHFR
DHFR 		0.310 Biomarker disease CTD_human Here, we report that the 19bp-deletion polymorphism of DHFR acts independently (OR 2.69, 95% CI; 1.00-7.28, p<0.05) and in concert with related folate polymorphisms as a significant risk factor for autism. 17597297 2007
Entrez Id: 205428
Gene Symbol: DIPK2A
DIPK2A 		0.320 Biomarker disease CTD_human Identifying autism loci and genes by tracing recent shared ancestry. 18621663 2008
Entrez Id: 27185
Gene Symbol: DISC1
DISC1 		0.380 Biomarker disease CTD_human We established association between autism and a DISC1 intragenic microsatellite (D1S2709; P=0.004). 17579608 2008
Entrez Id: 27185
Gene Symbol: DISC1
DISC1 		0.380 Biomarker disease CTD_human The duplication contains seven genes including the DISC1 gene, an interesting candidate gene that has been associated to schizophrenia, bipolar disorder, autism and Asperger syndrome. 20002455 2010
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1 		0.310 Biomarker disease CTD_human Analysis of DIXDC1 in over 9000 cases of autism, bipolar disorder and schizophrenia reveals higher rates of rare inherited sequence-disrupting single-nucleotide variants (SNVs) in these individuals compared with psychiatrically unaffected controls. 27752079 2018
Entrez Id: 9228
Gene Symbol: DLGAP2
DLGAP2 		0.320 Biomarker disease CTD_human Functional impact of global rare copy number variation in autism spectrum disorders. 20531469 2010
Entrez Id: 28514
Gene Symbol: DLL1
DLL1 		0.300 Biomarker disease GENOMICS_ENGLAND Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders. 31353024 2019
Entrez Id: 1745
Gene Symbol: DLX1
DLX1 		0.310 Biomarker disease CTD_human We investigated 6 Tag SNPs within the DLX1/2 genes in two cohorts of multiplex (MPX) and one of simplex (SPX) families for association with autism. 18728693 2009
Entrez Id: 1746
Gene Symbol: DLX2
DLX2 		0.320 Biomarker disease CTD_human The DLX1 and DLX2 genes lie head-to-head in 2q32, a region associated with autism susceptibility. 18728693 2009
Entrez Id: 9732
Gene Symbol: DOCK4
DOCK4 		0.350 Biomarker disease CTD_human Evidence for the involvement of DOCK4 in autism susceptibility was supported by independent replication of association at rs2217262 and the finding of a deletion segregating in a sib-pair family. 19401682 2010
Entrez Id: 1806
Gene Symbol: DPYD
DPYD 		0.400 Biomarker disease CTD_human Hemizygous deletions on chromosome 1p21.3 involving the DPYD gene in individuals with autism spectrum disorder. 21114665 2011
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.320 Biomarker disease CTD_human A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families. 18205172 2008
Entrez Id: 1814
Gene Symbol: DRD3
DRD3 		0.330 Biomarker disease CTD_human A common variant in DRD3 receptor is associated with autism spectrum disorder. 19058789 2009
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.320 Biomarker disease CTD_human Given the role of EGF in brain and neuronal development, we suggest a possible role of EGF in the pathogenesis of autism. 17626784 2007
Entrez Id: 1959
Gene Symbol: EGR2
EGR2 		0.310 Biomarker disease CTD_human Together, these data support a role of dysregulation of an activity-dependent EGR2/MeCP2 pathway in RTT and autism. 19000991 2009
Entrez Id: 1977
Gene Symbol: EIF4E
EIF4E 		0.320 Biomarker disease CTD_human