However, deletion of HMGCR specifically in T<sub>regs</sub> resulted in severe autoimmunity, suggesting that this enzyme is also essential for the maintenance of T<sub>regs</sub>.
Immune-mediated myopathy related to anti 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies as an emerging cause of necrotizing myopathy induced by statins.