| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | Taken together, these results indicated that DC-derived MMP-9 is the crucial factor for DC migration, and blocking MMP-9 to inhibit DC migration may constitute a novel strategy of future therapy for RA and other similar autoimmune diseases. | 30397034 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | Matrix metalloproteinase-9 (MMP-9) is closely related to the pathogenesis of autoimmune diseases, especially Systemic Lupus Erythematosus (SLE). | 29879882 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | We showed that increased levels of inflammatory biomarkers in patients with BP, such as CXCL10, favor neutrophil- and monocyte-associated MMP-9 release and disease relapse and opened new therapeutic horizons in patients with this autoimmune disease. | 27637385 | 2017 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Data from the present study suggest that the MMP-9 -1562 C/T polymorphism may be associated with multiple AD susceptibility, especially in the Caucasian populations and other ADs. | 28577863 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | Other genes with known involvement in autoimmunity such as MMP9 and PDGFRA were also hypomethylated. | 21436623 | 2011 | ||||
|
0.080 | AlteredExpression | group | LHGDN | This feature of MMP-9 along with its involvement in disease pathogenesis turns it into a target for therapy of autoimmune diseases. | 16652230 | 2006 | ||||
|
0.080 | Biomarker | group | BEFREE | This feature of MMP-9 along with its involvement in disease pathogenesis turns it into a target for therapy of autoimmune diseases. | 16652230 | 2006 | ||||
|
0.080 | Biomarker | group | BEFREE | We demonstrate that a Plg cascade synergizes with MMP-9/gelatinase B in vivo during dermal-epidermal separation in an experimental model of bullous pemphigoid (BP), an autoimmune disease. | 15841177 | 2005 | ||||
|
0.080 | Biomarker | group | BEFREE | Gelatinase B or matrix metalloproteinase (MMP)-9 is a proteinase establishing various disease-promoting feedback loops in autoimmune diseases. | 12965253 | 2003 |