Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE Our aim was to measure the clinical usefulness of quantitative CD64 measurement on neutrophils and soluble TREM-1 measurements in differentiating bacterial infection from active disease in patients with SLE and ANCA vasculitis. 30446886 2019
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE Triggering receptor expressed on myeloid cells (TREM-1) is a cell-surface receptor involved in amplification of inflammatory response to bacterial infections, along with its ligand peptidoglycan recognition protein 1 (PGLYRP1). 28846062 2018
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE Triggering receptor expressed on myeloid cells 1 (TREM-1), which amplifies the inflammation elicited by the Toll-like receptor pathway, was originally implicated in sepsis and bacterial infection. 26320130 2016
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE The gene expression levels of TREM1 in PMNs isolated from patients with bacterial infections may be used as a surrogate biomarker for determining the severity. 24465168 2014
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 AlteredExpression group BEFREE Evaluation of TREM1 gene expression in circulating polymorphonuclear leukocytes and its inverse correlation with the severity of pathophysiological conditions in patients with acute bacterial infections. 22996209 2012
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE Diagnostic value of the soluble triggering receptor expressed on myeloid cells-1 in bacterial infection: a meta-analysis. 18936908 2009
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE These data show that TREM-1 exerts a protective role in the innate immune response to a common bacterial infection and suggest that caution should be exerted in modulating TREM-1 activity during certain clinically relevant bacterial infections. 19596984 2009
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 AlteredExpression group BEFREE Here, we discuss the current state of the literature on TREMs, with a focus on TREM-1 and TREM-2 and their expression, signaling in mononuclear phagocytes and roles in innate immunity and bacterial infection. 18926286 2008
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
0.090 Biomarker group BEFREE Blockade of TREM-1 reduces inflammation and increases survival in animal models of bacterial infections that cause systemic hyperinflammatory syndromes.The TREM-1 ligands are not known. 12792857 2003