Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
0.500 CausalMutation disease CLINVAR
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
0.180 CausalMutation disease CLINVAR
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
0.150 CausalMutation disease CLINVAR
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1
0.120 CausalMutation disease CLINVAR
Entrez Id: 51816
Gene Symbol: ADA2
ADA2
0.110 CausalMutation disease CLINVAR
Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
0.010 Biomarker disease BEFREE <b>Abbreviations</b>: BD: Behçet's disease; EV: extracellular vesicle; BB: binding buffer; AnV: annexin V; autologEV: autologous extracellular vesicles; alloEV: allogeneic extracellular vesicles. 28326169 2017
Entrez Id: 442900
Gene Symbol: MIR326
MIR326
0.010 Biomarker disease BEFREE <b>Conclusion:</b> MiR-326 expression rate can be used as a biomarker for prediction of uveitis and severe eye involvement in patients with BD. 31599663 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.090 Biomarker disease BEFREE <b>Results:</b> Enrolled cases were divided to 26 patients with active uveitis, 25 patients with recovered uveitis and 24 patients without uveitis and interestingly, just IL-2 was the only cytokine that showed statistical difference in patients with BD uveitis in comparison with other groups (<i>p</i><sub>value</sub> = 0.02). 28468317 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.020 AlteredExpression disease BEFREE <b>Results:</b> Our results demonstrated significantly lower expression of miR-21 and miR-146b and higher expression of miR-326 in BD patients. 31599663 2019
Entrez Id: 574447
Gene Symbol: MIR146B
MIR146B
0.010 AlteredExpression disease BEFREE <b>Results:</b> Our results demonstrated significantly lower expression of miR-21 and miR-146b and higher expression of miR-326 in BD patients. 31599663 2019
Entrez Id: 2147
Gene Symbol: F2
F2
0.100 GeneticVariation disease BEFREE 27 previous studies analyzed the association of BD and thrombosis with the FVL, prothrombin and MTHFR polymorphisms. 23207285 2013
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.090 GeneticVariation disease BEFREE 27 previous studies analyzed the association of BD and thrombosis with the FVL, prothrombin and MTHFR polymorphisms. 23207285 2013
Entrez Id: 2023
Gene Symbol: ENO1
ENO1
0.040 Biomarker disease LHGDN BD patient sera positive for anti-alpha-enolase did not react with human gamma-enolase. 12847697 2003
Entrez Id: 2023
Gene Symbol: ENO1
ENO1
0.040 Biomarker disease BEFREE BD patient sera positive for anti-alpha-enolase did not react with human gamma-enolase. 12847697 2003
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.380 GeneticVariation disease BEFREE Behçet's disease was associated with the ICAM1 E469, genotype ICAM1 469 E/E, ICAM1 241 G/R polymorphisms in different ethnic groups. 24645721 2014
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
0.400 Biomarker disease BEFREE Behçet's disease (BD) is an immune-mediated and complex disease which has been associated with HLA class I molecules although other genes such as IL23R and IL10 have also been involved in the susceptibility to BD. 26005883 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.700 Biomarker disease BEFREE Behçet's disease (BD) is an immune-mediated and complex disease which has been associated with HLA class I molecules although other genes such as IL23R and IL10 have also been involved in the susceptibility to BD. 26005883 2016
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.700 GeneticVariation disease BEFREE Behçet's disease (BD), a multi-organ inflammatory disorder, is associated with the presence of the human leukocyte antigen (HLA) HLA-B*51 allele in many ethnic groups. 26331842 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.700 GeneticVariation disease BEFREE Behçet's disease (BD) susceptibility had been associated with single-nucleotide polymorphisms (SNPs) in IL23R-IL12RB2, IL10, STAT4, or ERAP1 locus in Japanese, Turkish, Chinese, and other populations, but not in a Korean genome-wide association study (GWAS). 29017598 2017
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
0.670 GeneticVariation disease BEFREE Behçet's disease (BD) susceptibility had been associated with single-nucleotide polymorphisms (SNPs) in IL23R-IL12RB2, IL10, STAT4, or ERAP1 locus in Japanese, Turkish, Chinese, and other populations, but not in a Korean genome-wide association study (GWAS). 29017598 2017
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
0.700 GeneticVariation disease BEFREE Behçet's disease (BD) susceptibility had been associated with single-nucleotide polymorphisms (SNPs) in IL23R-IL12RB2, IL10, STAT4, or ERAP1 locus in Japanese, Turkish, Chinese, and other populations, but not in a Korean genome-wide association study (GWAS). 29017598 2017
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.700 Biomarker disease BEFREE Behçet's disease was associated with HLA-A*24 and HLA-B*42 (p = 0.001) and highly associated with HLA-A*68 and B*15 and B*51 (p < 0.001). 30260727 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.700 GeneticVariation disease BEFREE Behçet's disease and genetic interactions between HLA-B*51 and variants in genes of autoinflammatory syndromes. 30808881 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.700 GeneticVariation disease BEFREE HLA-B*51 and B*15 alleles confer predisposition to Behçet's disease in Moroccan patients. 11182229 2001
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.700 Biomarker disease BEFREE HLA-B*51 does not exhibit a strong association with a more severe disease course in BD. 11426025 2001