Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100507436
Gene Symbol: MICA
MICA 		0.200 GeneticVariation disease BEFREE MICA gene polymorphisms in an Italian paediatric series of juvenile Behçet disease. 12373294 2002
Entrez Id: 100507436
Gene Symbol: MICA
MICA 		0.200 Biomarker disease BEFREE MICA is reported to be strongly associated with Behçet's disease (BD), a multisysytemic inflammation disorder characterized by oral apthous ulcers, skin lesions and genital ulcers. 12753668 2003
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.090 GeneticVariation disease BEFREE Methylenetetrahydrofolate reductase gene C677T mutation and plasma homocysteine level in Behçet's disease. 14504916 2003
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.100 GeneticVariation disease BEFREE Endothelial nitric oxide synthase gene polymorphisms in Behçet's disease and rheumatic diseases with vasculitis. 14583572 2003
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		0.500 GeneticVariation disease BEFREE MEFV mutations are increased in Behçet's disease (BD) and are associated with vascular involvement. 14727457 2004
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.100 GeneticVariation disease BEFREE eNOS gene polymorphisms are associated with BD, which might contribute to the reduced NO activity observed in BD patients. 15705632 2005
Entrez Id: 3593
Gene Symbol: IL12B
IL12B 		0.050 GeneticVariation disease BEFREE Interleukin-12B heterozygosity is associated with Behçet's disease susceptibility and plays an important role in mediating T helper type 1 antistreptococcal immune response. 18281862 2008
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C 		0.010 AlteredExpression disease BEFREE BAFF-R expression on B cells was increased in BD patients with vasculitis. 19026118 2009
Entrez Id: 3812
Gene Symbol: KIR3DL2
KIR3DL2 		0.040 GeneticVariation disease BEFREE Killer cell immunoglobulin-like receptor genotypes in Behçet's disease patients: any role for the 3DP1*001/002 pseudogene? 19405872 2009
Entrez Id: 3806
Gene Symbol: KIR2DS1
KIR2DS1 		0.030 GeneticVariation disease BEFREE Killer cell immunoglobulin-like receptor genotypes in Behçet's disease patients: any role for the 3DP1*001/002 pseudogene? 19405872 2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.100 GeneticVariation disease BEFREE eNOS gene polymorphisms associated with BD are not associated with RAS. 19410237 2009
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		0.020 GeneticVariation disease BEFREE IkappaBalpha promoter polymorphisms in patients with Behçet's disease. 20164548 2010
Entrez Id: 51561
Gene Symbol: IL23A
IL23A 		0.080 Biomarker disease BEFREE IL-23 has been shown to be involved in the pathogenesis of Behcet's disease (BD) through promoting IL-17 production. 20375120 2010
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		0.100 Biomarker disease BEFREE HLA-A*02:07, A*26:01, and A*30:04 were associated with increased risk for BD, while HLA-A*33:03 with decreased risk. 21429233 2011
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		0.500 Biomarker disease BEFREE MEFV gene analysis was performed in all the patients with BD and healthy controls; twelve different regions were scanned. 21901355 2012
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13 		0.020 Biomarker disease BEFREE IFN-α had been used clinically in treating BD with uveitis with beneficial efficacy ever since the 1980s. 22197901 2012
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1 		0.020 Biomarker disease BEFREE IFN-α had been used clinically in treating BD with uveitis with beneficial efficacy ever since the 1980s. 22197901 2012
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3 		0.090 GeneticVariation disease BEFREE TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population. 23161053 2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.100 Biomarker disease BEFREE IL-1β and ROS production of peptidoglycan (PGN)/lipopolysaccharide (LPS)-induced MDMs from active BD patients was significantly increased compared with inactive BD patients, AAU patients, and healthy controls. 23211828 2013
Entrez Id: 79001
Gene Symbol: VKORC1
VKORC1 		0.010 GeneticVariation disease BEFREE VKORC1 polymorphisms seem not to be related with the thrombotic state of systemic and ocular Behçet's disease. 23362849 2014
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.010 Biomarker disease BEFREE SIRT1 activator treatment in vitro using mouse pLN cells, normal human and ocular Behçet's disease donor PBMC resulted in suppressed T cell proliferation and pro-inflammatory cytokine production. 23395551 2013
Entrez Id: 2069
Gene Symbol: EREG
EREG 		0.010 GeneticVariation disease BEFREE EREG-AREG and NRG1, which are members of the epidermal growth factor (EGF) family, seem to modulate BD susceptibility through main effects and gene-gene interactions. 23625463 2013
Entrez Id: 114609
Gene Symbol: TIRAP
TIRAP 		0.020 GeneticVariation disease BEFREE TIRAP S180L gene polymorphism, which was previously shown to be associated with BD in a Caucasian population, has been replicated in either Turkish or Italian population in our study. 24064014 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.700 Biomarker disease BEFREE IL10 may be the susceptibility gene for BD in Chinese Han population. 24269690 2014
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		0.100 Biomarker disease BEFREE HLA-A*26 was claimed as an additional BD susceptibility marker in Japanese and Greek patients. 24887019 2014