Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | HLA genes show a strong association with both VKH disease (HLA-DR4, DRB1/DQA1) and BD (HLA-B51) in multiple ethnic populations. | 31669406 | 2020 | ||||
|
0.070 | Biomarker | disease | BEFREE | The aim of this review is to provide a brief overview of the role and current clinical relevance of HLA-B27 in spondyloarthritis and HLA-B51 in Behcet's disease as well as HLA-DQ2/DQ8 in celiac disease and HLA-DRB1 in rheumatoid arthritis and to discuss possible future implications. | 29858799 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | It is noteworthy that in Sardinia this allele was found more frequently within a haplotype (HLA-A2; -Cw2; -B*5101; -DRB1*11; -DQA1*05; - DQB1*03) that reached its highest frequency in patients with BD. | 23021043 | 2013 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The results suggested that HLA-DRB1 alleles might play an important role in the onset and clinical manifestations of BD. | 20205319 | 2009 | ||||
|
0.070 | Biomarker | disease | BEFREE | A significant increased frequency of HLA-B(*)44 (P = 0.02; OR = 2.78; CI 95% = 1.1-7.7), HLA-B(*)52 (P = 0.02; OR = 5.33; CI 95% = 1.07-29.1), and HLA-B(*)56 (P = 0.003; OR = 4.19; CI 95% = 3.37-5.21) as well as HLA-DRB1(*)01 and HLA-DRB1(*)13 (p = 0.007; OR = 3.36; CI 95% = 1.22-9.27) was found in Mexican patients with Behçet's disease when compared to controls. | 15158619 | 2004 | ||||
|
0.070 | Biomarker | disease | LHGDN | Class I and class II MHC polymorphisms in Mexican patients with Behçet's disease. | 15158619 | 2004 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Thirteen Saudi Arabian patients with Behçet's disease (BD) were typed for HLA-A and -B alleles by the conventional serologic typing and for HLA-DRB1, -DQB1 and -DPB1 alleles by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. | 10519364 | 1999 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | To determine if susceptibility to Behçet's disease (BD) is associated with polymorphism of HLA-DRB1, HLA-DQB1, DQB1, and TAP1 and TAP2 genes. | 7794046 | 1995 |