Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | This study aimed to investigate the contribution of certain KIR functional polymorphisms to the susceptibility to BD. | 31849952 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | To our knowledge, this is the first analysis of KIR3DL1/S1 allelic variation in Behçet disease and may provide insight into the pathogenic role of <i>HLA-B*51</i> and its interaction with KIR3DL1/S1. | 31405953 | 2019 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | None of the KIR genes showed significant effects on BD susceptibility. | 28862099 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | We tested whether KIR-regulated mechanisms contribute to BD by testing for association of KIR3DL1/KIR3DS1 genotypes with disease in 1799 BD patients and 1710 healthy controls from Turkey, as well as in different subsets of individuals with HLA-type-defined ligands for the KIR3D receptors. | 27708262 | 2016 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The authors analyzed the frequency of 16 KIR genes in Koreans with either AS (110 patients, all HLA-B27-positive) or BD (86 patients), using polymerase chain reaction sequence-specific oligonucleotide probing. | 23697859 | 2013 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | There was no statistically significant distribution of the different KIR genes between the cases (BD patients) and controls (Lebanese population); however, KIR3DP1*001/002 was found to be significantly different between the BD patients and the Lebanese population, but this significance was lost after correction for all KIR loci. | 19405872 | 2009 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Thus, no association was identified between presence or absence of any of the 14 KIR genes studied and BD. | 17868255 | 2007 | ||||
|
0.080 | Biomarker | disease | BEFREE | Selective increase of B*2702, the only B*27 allele carrying the same KIR binding sequence with B*51, warrants investigation of the possibility of interaction of HLA molecules with KIRs on NK or other T cells in the pathogenesis of BD. | 12209364 | 2002 |