| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | The index case and the two daughters with Behçet-like disease, were previously found to have a TNFAIP3 frameshift mutation. | 31376265 | 2020 | ||||
|
0.090 | Biomarker | disease | BEFREE | It has recently been recognized that TNFAIP3 deficiency leads to early onset of autoinflammatory and autoimmune syndrome resembling Behçet's disease. | 30810840 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Genetic screening of TNFAIP3 should be considered for familial BD-like patients with early-onset recurrent fevers. | 31164164 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Further functional studies are required to research whether the variant of TNFAIP3 plays a part in the development of GPP or simply causes the Behçet's disease phenotype. | 31353537 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Mutations in tumor necrosis factor α-induced protein 3 results in a disease that can present as Behçet disease called haploinsufficiency of A20. | 28582318 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Lack of association of TNFAIP3 and JAK1 with Behçet's disease in the European population. | 26005883 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | These associations include ERAP1, CCR1-CCR3, STAT4, KLRC4, GIMAP4, and TNFAIP3 in Behçet's disease; BLK and CD40 in Kawasaki disease; SERPINA1 and SEMA6A in antineutrophil cytoplasmic antibody associated vasculitides; IL12B and FCGR2A/ FCGR2A in Takayasu arteritis; and CECR1 in a newly defined vascular inflammatory syndrome associated with adenosine deaminase (ADA2) deficiency. | 25405820 | 2015 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The aim of the study was to investigate the association of TNFα-induced protein 3 interacting with protein 1 (TNIP1) gene polymorphisms with Vogt-Koyanagi-Harada (VKH) syndrome and Behcet's disease (BD) in a Han Chinese population. | 24788730 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population. | 23161053 | 2013 |