Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 AlteredExpression disease BEFREE ADD3, verified as a target of miR-145-5p, was shown to be overexpressed in infants with BA at the mRNA level (p = 0.0118). 28902846 2017
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 GeneticVariation disease BEFREE This study suggests that the ADD3 gene plays an important role in BA pathogenesis and reveals a significant association between two SNPs, rs17095355 and rs10509906, and BA. 25285724 2014
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 GeneticVariation disease BEFREE ADD3 and ADD3-AS1 variants increased susceptibility to BA, suggesting that these genes may play an additive role in the pathogenesis of the disease. 29508064 2018
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 GeneticVariation disease BEFREE As a member of membrane skeletal proteins in the liver and bile ducts, a haplotype composed by five single nucleotide polymorphisms (SNPs) on adducin 3 (<i>ADD3</i>) has been identified as associated with BA. 29685956 2018
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 Biomarker disease BEFREE The role of ADD3 in biliary development is unclear, but our findings suggest that this gene may be functionally relevant for the development of BA. 24104524 2014
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.060 AlteredExpression disease BEFREE Moreover, in bioinformatics and in vivo genotype-expression investigations, the BA-associated potentially regulatory SNPs correlated with ADD3 gene expression (n=36; p=0.0030). 23872602 2013