Gene: CLOCK ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 AlteredExpression disease BEFREE Lithium response in bipolar disorders and core clock genes expression. 28095742 2018
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 PosttranslationalModification disease BEFREE The current investigation aimed at analyzing the correlation between gut microbiome diversity and the methylation of the clock gene ARNTL in individuals with Bipolar Disorder (BD). 30465968 2019
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease BEFREE Therefore, we conducted an analysis of the relationship between clock genes (as distal risk factors) with clinical characteristics and the course of bipolar disorder. 28837935 2017
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease LHGDN This preliminary observation leads to hypothesize a role for the CLOCK gene polymorphism in the regulation of long-term illness recurrence in bipolar disorder. 14582141 2003
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease MGD
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease PSYGENET Clock genes have been implicated in several disorders, such as schizophrenia, bipolar disorder, autism spectrum disorders, and drug dependence. 24865659 2014
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease PSYGENET We genotyped 42 polymorphisms from circadian clock genes: PER3, ARNTL, CLOCK and TIMELSSS from 511 patients BD (n = 292 women and n = 219 men). 24673294 2014
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease PSYGENET Suicidal behavior in the context of disrupted rhythmicity in bipolar disorder--data from an association study of suicide attempts with clock genes. 25724486 2015
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease PSYGENET Polymorphism of circadian clock genes and temperamental dimensions of the TEMPS-A in bipolar disorder. 24679394 2014
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease PSYGENET Since stressful life events or increased vulnerability to stress are risk factors for multiple psychiatric disorders, including post-traumatic stress disorder (PTSD), attention deficit hyperactivity disorder (ADHD), bipolar disorder (BD), major depressive disorder (MDD), alcohol use disorder (AUD) and schizophrenia (SCZ), we propose that modulation of the stress response is a common mechanism by which circadian clock genes affect these illnesses. 25135782 2014