| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.330 | Biomarker | disease | PSYGENET | Significant association of estrogen receptor binding site variation with bipolar disorder in females. | 22389694 | 2012 | ||||
|
0.330 | GeneticVariation | disease | BEFREE | Significant association of estrogen receptor binding site variation with bipolar disorder in females. | 22389694 | 2012 | ||||
|
0.330 | Biomarker | disease | PSYGENET | Estrogen receptor alpha mRNA levels were reduced in the basomedial nucleus in major depressive disorder and bipolar disorder. | 15576061 | 2004 | ||||
|
0.330 | AlteredExpression | disease | BEFREE | Estrogen receptor alpha mRNA levels were reduced in the basomedial nucleus in major depressive disorder and bipolar disorder. | 15576061 | 2004 | ||||
|
0.330 | AlteredExpression | disease | LHGDN | Estrogen receptor alpha mRNA levels were reduced in the basomedial nucleus in major depressive disorder and bipolar disorder. | 15576061 | 2004 | ||||
|
0.330 | Biomarker | disease | PSYGENET | The estrogen receptor alpha (ERalpha) gene in particular has been a subject of interest and has recently been intensively screened for variations of potential relevance to psychiatric disorders, resulting in the identification of four mutations in individuals with bipolar disorder or puerperal psychosis. | 12627470 | 2003 | ||||
|
0.330 | Biomarker | disease | PSYGENET | As the effects of oestrogen are most probably mediated through the oestrogen receptors (ER alpha and ER beta), the genes encoding these receptors may be possible candidates for association studies with bipolar disorder and other neuropsychiatric disorders. | 11807414 | 2001 | ||||
|
0.330 | Biomarker | disease | PSYGENET | We have undertaken a case control association study of bipolar disorder and puerperal psychosis at two known polymorphisms within the estrogen receptor alpha gene (ESR 1) in a sample of 219 unrelated bipolar probands and 219 controls. | 11121195 | 2000 | ||||
|
0.330 | GeneticVariation | disease | BEFREE | Molecular genetic studies of bipolar disorder and puerperal psychosis at two polymorphisms in the estrogen receptor alpha gene (ESR 1). | 11121195 | 2000 |