Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
0.320 Biomarker disease BEFREE Brain 5-HT1A binding potential (BP(F) = B(max)/K(D), where B(max) = total available receptors, and 1/K(D) = ligand affinity) was measured in 32 currently depressed, medication-free BD subjects and 47 controls. 19278673 2009
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.310 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 GeneticVariation disease BEFREE Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Ca<sub>v</sub> 1.2, is associated with clinical diagnoses of bipolar disorder, depression and schizophrenia. 28186690 2017
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.310 GeneticVariation disease BEFREE Glycogen synthase kinase 3 beta gene structural variants as possible risk factors of bipolar depression. 24677591 2014
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.310 Biomarker disease PSYGENET Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.310 Biomarker disease BEFREE Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.310 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.310 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
0.310 AlteredExpression disease BEFREE We also quantified the expression levels of WFS1 mRNA in the postmortem brains of patients with bipolar disorder, depression, schizophrenia, and controls. 12565131 2003
Entrez Id: 5091
Gene Symbol: PC
PC
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 57519
Gene Symbol: STARD9
STARD9
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 51177
Gene Symbol: PLEKHO1
PLEKHO1
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 51650
Gene Symbol: MRPS33
MRPS33
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 22941
Gene Symbol: SHANK2
SHANK2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 6733
Gene Symbol: SRPK2
SRPK2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9881
Gene Symbol: TRANK1
TRANK1
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 2903
Gene Symbol: GRIN2A
GRIN2A
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9415
Gene Symbol: FADS2
FADS2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 55690
Gene Symbol: PACS1
PACS1
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9640
Gene Symbol: ZNF592
ZNF592
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 5454
Gene Symbol: POU3F2
POU3F2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019