Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.310 GeneticVariation disease UNIPROT
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.300 Biomarker disease MGD
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
0.300 CausalMutation disease CGI
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.300 Biomarker disease MGD
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
0.300 GenomicAlterations disease CGI
Entrez Id: 79718
Gene Symbol: TBL1XR1
TBL1XR1
0.300 CausalMutation disease CGI
Entrez Id: 23385
Gene Symbol: NCSTN
NCSTN
0.200 Biomarker disease MGD
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
0.100 GeneticVariation disease CLINVAR
Entrez Id: 1290
Gene Symbol: COL5A2
COL5A2
0.020 Biomarker disease BEFREE "Our results demonstrated that COL5A2 was correlated with poor clinical outcomes and survivals of patients with bladder cancer, suggesting that it could be regarded as a biomarker of bladder cancer. 29517678 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
0.300 GeneticVariation disease BEFREE <b>Aims:</b> Whether pioglitazone (PIO), a peroxisome proliferator-activated receptor-gamma agonist, increases the risk of developing bladder cancer has been debated for several years. 29483814 2018
Entrez Id: 652995
Gene Symbol: UCA1
UCA1
0.100 Biomarker disease BEFREE <b>Background:</b> Urothelial carcinoma associated 1 (UCA1), a novel long noncoding RNA (lncRNA) which is first discovered in 2006 in human bladder cancer and has become a hot spot in recent years. 30918102 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
0.290 Biomarker disease BEFREE <b>Conclusion:</b> MicroRNA-124 suppressed the proliferation of CRC cells by directly targeting CDK4, which provides a target for improving the therapeutic effect of BC. 31190856 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
0.030 Biomarker disease BEFREE <b>Conclusion:</b> This study not only demonstrated the great potential of HSA-MnO<sub>2</sub>-Ce6 NPs for bladder cancer photodynamic ablation but also provided a new therapeutic strategy to overcoming tumor hypoxia. 29463995 2018
Entrez Id: 5018
Gene Symbol: OXA1L
OXA1L
0.010 Biomarker disease BEFREE <b>Conclusion:</b> This study not only demonstrated the great potential of HSA-MnO<sub>2</sub>-Ce6 NPs for bladder cancer photodynamic ablation but also provided a new therapeutic strategy to overcoming tumor hypoxia. 29463995 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.100 AlteredExpression disease BEFREE <b>Conclusions:</b> Expression of PD-L1 on TCs was associated with muscle-invasive disease in patients with bladder cancer. 31190987 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.100 AlteredExpression disease BEFREE <b>Conclusions:</b> The meta-analysis suggested that PD-L1 overexpression could predict worse survival outcomes in bladder cancer. 31616289 2019
Entrez Id: 406921
Gene Symbol: MIR132
MIR132
0.020 AlteredExpression disease BEFREE <b>Methods:</b> miR-132 expression level was assessed by quantitative real-time PCR (qRT-PCR) in 32 BC tissues and BC cell lines (T24). 31413591 2019
Entrez Id: 51320
Gene Symbol: MEX3C
MEX3C
0.010 AlteredExpression disease BEFREE <b>Results:</b> MEX3C was highly expressed in BC tissues and cells compared with their normal counterparts, and its expression was positively correlated with the clinicopathological features, especially the invasiveness phenotype. 31118679 2019
Entrez Id: 11051
Gene Symbol: NUDT21
NUDT21
0.010 AlteredExpression disease BEFREE <b>Results:</b> NUDT21 expression is reduced in BC tissue and cells, and BC patients with lower NUDT21 expression have shorter overall and recurrent-free survival than patients with higher NUDT21 expression. 31695759 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.050 Biomarker disease BEFREE <i>Conclusions</i>: FDG PET/CT has the potential to change patient management, particularly for patients with BC. 31137599 2019
Entrez Id: 652
Gene Symbol: BMP4
BMP4
0.030 Biomarker disease BEFREE <i>In vitro</i> experiments showed that both recombinant BMP4 and BMP4-containing conditioned media from bladder cancer cell lines favored monocyte/macrophage polarization toward M2 phenotype macrophages, as shown by the expression and secretion of IL10. 28928159 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.100 GeneticVariation disease BEFREE (p) ran in particular produced exciting results when coupled with a version of the caspase 3 exon to treat bladder cancer. 27140445 2016
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
0.800 GeneticVariation disease BEFREE 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest. 19955487 2010
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
0.050 GeneticVariation disease BEFREE 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest. 19955487 2010
Entrez Id: 10519
Gene Symbol: CIB1
CIB1
0.010 GeneticVariation disease BEFREE 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest. 19955487 2010