Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 Biomarker disease BEFREE Taken together, these findings define a tumor-supportive role for TACC3, which may also serve as a prognostic and therapeutic indicator in bladder cancers. 29358577 2018
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease BEFREE Association between the TACC3 rs798766 Polymorphism and Risk of Urinary Bladder Cancer: A Synthesis Based on Current Evidence. 28655970 2017
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 Biomarker disease BEFREE FGFR3-TACC3 fusion transcripts were identified by RNA-FISH and RT-PCR in mouse xenograft FFPE tissues using the human BC cell lines RT112 and RT4. 27930669 2016
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease BEFREE When we examined detailed data on a prevalent occupational exposure associated with increased bladder cancer risk, straight metalworking fluids, we also observed statistically significant additive interaction for rs798766 (TMEM129-TACC3-FGFR3, P interaction = .02), with the interaction more apparent in patients with tumors positive for FGFR3 expression.All statistical tests were two-sided. 26374428 2015
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease GWASDB Genome-wide association study identifies multiple loci associated with bladder cancer risk. 24163127 2014
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease BEFREE Three previously established bladder cancer risk-associated SNPs (rs798766 in TACC3, rs9642880 in MYC, and rs2294008 in PSCA) were genotyped in 1,210 bladder cancer patients and 1,008 control subjects in Shanghai, China. 24155119 2014
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 Biomarker disease CTD_human Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. 24121792 2013
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease BEFREE In the meta-analysis, the reported risk allele for four SNPs were significantly associated with increased bladder cancer risk, including rs798766 on TACC3 at 4p16, rs9624880 on MYC at 8q24, rs2294008 on PSCA at 8q24, and rs2736100 on TERT at 5p15. 22711262 2013
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease GWASDB A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. 20348956 2010
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease BEFREE The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio = 1.24, P = 9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70 kb from FGFR3, which often harbors activating somatic mutations in low-grade, noninvasive UBC. 20348956 2010
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
0.470 GeneticVariation disease GWASDB A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010