| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | The long non-coding RNA (lncRNA) X inactive specific transcript (XIST) has recently been reported to promote the malignant progression of bladder cancer through regulating several microRNAs (miRs), including miR-124, miR-139-5p and miR-200c. | 31602223 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. | 31240993 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | LncRNA XIST may act as an inhibitor of miR-200c to regulate the stemness properties and tumourigenicity of bladder cancer cells, and our findings might reveal a potential strategy of targeting XIST for bladder cancer therapy. | 29559853 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Thus, targeting LDHA through miR-200c is a potential therapeutic strategy in bladder cancer. | 28978061 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Collectively, our studies demonstrate that RhoGDIβ overexpression inhibits miR-200c abundance, which consequently results in increases of JNK2 protein translation, Sp1 expression, mmp-2 transcription, and BC invasion. | 28846829 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Association between tissue miR-141, miR-200c and miR-30b and bladder cancer: a matched case-control study. | 25703910 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Real-time reverse transcription-PCR was used to identify and validate the differential expression of MiR-200c involved in EMT in 4 bladder cancer cell lines and clinical specimens. | 25367080 | 2014 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Moreover, we report that miR-200c expression is significantly correlated with early stage T1 bladder tumor progression, and propose miR-200 and miR-205 silencing and DNA hypermethylation as possible prognostic markers in bladder cancer. | 20473948 | 2011 |