| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Transfection of miR-34a mimics upregulated the expression of phosphatase and tensin homolog (PTEN) in bladder cancer cells, and decreased cell migration and invasion. miR-34a may inhibit bladder cancer cell migration and invasion by upregulating PTEN. miR-34a may additionally serve as a potential therapeutic target for bladder cancer. | 31612063 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In addition, the expression of miR‑34a was inversely correlated with the expression of MALAT1 in BC tissues. | 30387807 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | The miR-34a profiles in bladder cancer tissues were obtained from The Cancer Genome Atlas database. | 30001529 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | We leveraged our unique, large, population-based prognostic study of bladder cancer in New Hampshire, United States to evaluate miR-34a expression levels in individual tumor cells to assess prognostic value. | 25556547 | 2015 | ||||
|
0.080 | Biomarker | disease | BEFREE | This study explored the regulative role of miR-34a on an orphan nuclear receptor HNF4G, which has a well-confirmed role in bladder tumor growth and invasion. qRT-PCR analysis was applied to measure miR-34a expression in two tumorigenic bladder cancer cell lines 5637 and T24 and one normal human urothelial cell line SV-HUC-1. | 25878394 | 2015 | ||||
|
0.080 | Biomarker | disease | BEFREE | Our results provide sufficient evidence that polyphenols in PRE can be potential molecular clusters to suppress bladder cancer cell EJ proliferation via p53/miR-34a axis. | 25572695 | 2015 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we focus on it that microRNA-34a functions as an anti-metastatic microRNA and suppress angiogenesis in bladder cancer by directly targeting CD44. | 25551284 | 2014 | ||||
|
0.080 | Biomarker | disease | BEFREE | MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status. | 21702042 | 2012 |