Aberrant expression of lncRNA Taurine-upregulated gene 1 (TUG1) has been found to be involved in the development of bladder cancer, however, its function and underlying mechanism in the radioresistance of bladder cancer remains unclear.
In stratified analyses, a significantly unfavorable OS associated with elevated lncRNA TUG1 was observed in both bladder cancer (HR = 2.98, 95% CI: 1.84-4.83, P < 0.0001) and other system cancer (HR = 2.63, 95% CI: 1.42-4.87, P = 0.002), but not respiratory system cancer (HR = 0.93, 95% CI: 0.30-2.82, P = 0.895).