To investigate the changes of expression in both the nerve growth factor (NGF) and the angiotensin II type 1 (AT1) receptors in the urothelium and the detrusor muscle in a rat model of bladder outlet obstruction (BOO).
Nerve growth factor was associated with overactive bladder symptoms in patients with benign prostatic hyperplasia as well as with the assessment of successful long-term treatment outcome of bladder outlet obstruction with symptoms of overactive bladder.