×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
GeneticVariation
disease
BEFREE
Snap-frozen bladder tumors (n=99) of different stages and grades and 4 cell lines (RT4, RT112, J82, UROtsa) were investigated for APC allelic deletions by loss of heterozygosity (LOH) analysis.
11956582
2002
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
PosttranslationalModification
disease
BEFREE
In addition, the diagnostic sensitivity, specificity, and area under the curve (AUC) value of APC hypermethylation for bladder cancer were calculated.
30568459
2018
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
Biomarker
disease
BEFREE
Our findings indicate that APC promoter methylation may be associated with the development and progression of bladder cancer and may serve as a promising noninvasive biomarker using urine samples for the detection of bladder cancer .
30868894
2019
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
GeneticVariation
disease
BEFREE
Deletion analysis at the DEL-27, APC and MTS1 loci in bladder cancer : LOH at the DEL-27 locus on 5p13-12 is a prognostic marker of tumor progression.
9221807
1997
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
Biomarker
disease
BEFREE
RASSF1a/APC/p14, RAR_/DAPK/E-cadh/p16, p16/p14/MGMT/GSTP1, and RASSF1a/E-cadh/APC ) are of interest in the detection of bladder cancer .
19522860
2009
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
Biomarker
disease
BEFREE
We investigated the roles and possible interactions of the tumor suppressor genes p53, Rb, DCC and APC in bladder cancer .
8632608
1996
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
Biomarker
disease
BEFREE
Bladder cancer specific mortality was significantly increased in patients with APC hypermethylation.
18006010
2008
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.080
Biomarker
disease
BEFREE
Thus, methylated RARβ(2) and APC genes might be valuable urinary molecular markers for early detection of bilharzial and nonbilharzial bladder cancer .
21680534
2011