Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.500 GeneticVariation group BEFREE Future clinical trials should address whether BRAF (V600E) mutant brain tumor patients will benefit from BRAF (V600E)-directed targeted therapies. 21274720 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.500 GeneticVariation group BEFREE Emerging evidence support the effectiveness of targeted therapies for brain tumors with BRAF V600E mutation. 31345255 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.500 GeneticVariation group CLINVAR Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. 22586120 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.500 GeneticVariation group BEFREE Efficacy of BRAF V600E targeted therapies in brain tumors harboring the mutation has been shown in several case reports and is currently being studied in larger clinical trials. 29380516 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.500 Biomarker group BEFREE We report here that targeting a completely different process, autophagy, can overcome multiple BRAF inhibitor resistance mechanisms in brain tumors. 28094001 2017